Activating Compound | Comment | Organism | Structure |
---|---|---|---|
additional information | the enzyme is stimulated by the T-cell receptor | Homo sapiens |
Inhibitors | Comment | Organism | Structure |
---|---|---|---|
cyclosporin A | - |
Homo sapiens | |
tacrolimus | 27-30% inhibition at 5 ng/ml, females and males | Homo sapiens |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Homo sapiens | - |
- |
- |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
T-lymphocyte | - |
Homo sapiens | - |
Specific Activity Minimum [µmol/min/mg] | Specific Activity Maximum [µmol/min/mg] | Comment | Organism |
---|---|---|---|
additional information | - |
enzyme activity is much higher in mlaes compared to females, overview | Homo sapiens |
0.0000008 | 0.0000017 | T-cells from females and males, not stimulated and T-cell-stimulated | Homo sapiens |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
a phosphoprotein + H2O | - |
Homo sapiens | dephosphorylated protein + phosphate | - |
? |
Synonyms | Comment | Organism |
---|---|---|
calcineurin | - |
Homo sapiens |
Temperature Optimum [°C] | Temperature Optimum Maximum [°C] | Comment | Organism |
---|---|---|---|
37 | - |
assay at | Homo sapiens |
pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
---|---|---|---|
7.5 | - |
assay at | Homo sapiens |