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Literature summary for 3.1.3.11 extracted from
- Inhibition of fructose 1,6-bisphosphatase reduces excessive endogenous glucose production and attenuates hyperglycemia in Zucker diabetic fatty rats (2006), Diabetes, 55, 1747-1754.
Application
| Application | Comment | Organism |
|---|---|---|
| medicine | excessive gluconeogenesis plays an integral role in the pathophysiology of type 2 diabetes. FBPase inhibitors may provide a future treatment option | Rattus norvegicus |
Inhibitors
| Inhibitors | Comment | Organism | Structure |
|---|---|---|---|
| MB06322 | - |
Rattus norvegicus |  |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Rattus norvegicus | - |
Zucker diabetic fatty rats | - |
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