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Literature summary for 3.1.3.11 extracted from
- Amplified expression of fructose 1,6-bisphosphatase in Corynebacterium glutamicum increases in vivo flux through the pentose phosphate pathway and lysine production on different carbon sources (2005), Appl. Environ. Microbiol., 71, 8587-8596.
Application
| Application | Comment | Organism |
|---|---|---|
| synthesis | overexpression of enzyme increases the lysine yield by 40% for growth on glucose and by 30% for growth on fructose or sucrose. Overexpression causes a redirection of carbon flux from glycolysis toward the pentose pathway and thus leads to increased NADPH supply. Use of overexpression for starch- and molasses-based industrial lysine production | Corynebacterium glutamicum |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Corynebacterium glutamicum | - |
overexpression of enzyme in strains grown on different sugars | - |
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