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Literature summary for 3.1.3.1 extracted from

  • Manning, J.P.; Inglis, N.R.; Green, S.; Fishman, W.H.
    Characterization of placental alkaline phosphatase from the rabbit, guinea pig, mouse and hamster (1970), Enzymologia, 39, 307-318.
    View publication on PubMed

Inhibitors

Inhibitors Comment Organism Structure
Phe
-
Cavia porcellus
Phe
-
Mus musculus
Phe
-
Oryctolagus cuniculus

KM Value [mM]

KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
6.1
-
Phenyl phosphate
-
Oryctolagus cuniculus
9.5
-
Phenyl phosphate
-
Mus musculus
10.2
-
Phenyl phosphate
-
Mesocricetus auratus
12.4
-
Phenyl phosphate
-
Mus musculus

Organism

Organism UniProt Comment Textmining
Cavia porcellus
-
-
-
Mesocricetus auratus
-
-
-
Mus musculus
-
-
-
Oryctolagus cuniculus
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining
placenta
-
Cavia porcellus
-
placenta
-
Mus musculus
-
placenta
-
Oryctolagus cuniculus
-
placenta
-
Mesocricetus auratus
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
phenyl phosphate + H2O
-
Cavia porcellus phenol + phosphate
-
?
phenyl phosphate + H2O
-
Mus musculus phenol + phosphate
-
?
phenyl phosphate + H2O
-
Oryctolagus cuniculus phenol + phosphate
-
?
phenyl phosphate + H2O
-
Mesocricetus auratus phenol + phosphate
-
?

Temperature Stability [°C]

Temperature Stability Minimum [°C] Temperature Stability Maximum [°C] Comment Organism
55
-
16 min, 83% inactivation Mus musculus
55
-
16 min, 95% inactivation Cavia porcellus
55
-
16 min, 80% inactivation Oryctolagus cuniculus
55
-
16 min, complete inactivation Mesocricetus auratus

pH Optimum

pH Optimum Minimum pH Optimum Maximum Comment Organism
10.1
-
-
Oryctolagus cuniculus
10.2
-
-
Cavia porcellus
10.2
-
-
Mesocricetus auratus
10.2 10.3
-
Mus musculus

pH Range

pH Minimum pH Maximum Comment Organism
additional information
-
-
Cavia porcellus
additional information
-
-
Mus musculus
additional information
-
-
Oryctolagus cuniculus
additional information
-
-
Mesocricetus auratus