Any feedback?
Please rate this page
(literature.php)
(0/150)

BRENDA support

Literature summary for 3.1.3.1 extracted from

  • Fernley, H.N.
    Mammalian alkaline phosphatases (1971), The Enzymes, 3rd Ed. (Boyer, P. D. , ed. ), 4, 417-447.
No PubMed abstract available
Search for more literature for 3.1.3.1

General Stability

General Stability Organism
8 M urea, at 37°C, half-life of placental enzyme: 3 h. 3 M urea, half-life of the bone enzyme: 7 min Homo sapiens

KM Value [mM]

KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
0.8
-
 p-nitrophenyl phosphate
-
 Homo sapiens
1.4
-
 beta-Glycerophosphate
-
 Homo sapiens
2.9
-
 Phosphoethanolamine
-
 Homo sapiens
3
-
 5'-AMP
-
 Homo sapiens
4
-
 diphosphate
-
 Homo sapiens
4.4
-
 ADP
-
 Homo sapiens
4.8
-
 glucose 1-phosphate
-
 Homo sapiens
5.7
-
 ATP
-
 Homo sapiens

Metals/Ions

Metals/Ions Comment Organism Structure
Zn2+ the enzyme contains 0.15% Zn2+ Homo sapiens
Zn2+ calf enzyme contains 0.2% Zn2+ Bos taurus

Molecular Weight [Da]

Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
additional information
-
-
 Homo sapiens
additional information
-
-
 Bos taurus
additional information
-
-
 Equus caballus

Organism

Organism UniProt Comment Textmining
Bos taurus
-
 calf
-
Equus caballus
-
-
-
Homo sapiens
-
-
-

Posttranslational Modification

Posttranslational Modification Comment Organism
side-chain modification
-
 Homo sapiens
side-chain modification 26% carbohydrate Equus caballus
side-chain modification calf intestinal enzyme contains about 20% hexose + hexosamine Bos taurus

Source Tissue

Source Tissue Comment Organism Textmining
bone
-
 Homo sapiens
-
bone
-
 Bos taurus
-
intestine
-
 Homo sapiens
-
intestine intestinal mucosa Bos taurus
-
kidney
-
 Homo sapiens
-
kidney
-
 Equus caballus
-
liver
-
 Homo sapiens
-
liver
-
 Bos taurus
-
placenta
-
 Homo sapiens
-
placenta
-
 Bos taurus
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
2-phosphoglycerate + H2O
-
 Homo sapiens glycerol + phosphate
-
 ?
3-phosphoglycerate + H2O
-
 Homo sapiens glycerol + phosphate
-
 ?
4-methylumbelliferyl phosphate + H2O
-
 Homo sapiens 4-methylumbelliferone + phosphate
-
 ?
4-methylumbelliferyl phosphate + H2O
-
 Bos taurus 4-methylumbelliferone + phosphate
-
 ?
5'-AMP + H2O
-
 Homo sapiens adenosine + phosphate
-
 ?
5'-UMP + H2O
-
 Homo sapiens uridine + phosphate
-
 ?
ADP + H2O
-
 Homo sapiens ?
-
 ?
ATP + H2O
-
 Homo sapiens ?
-
 ?
ATP + H2O
-
 Bos taurus ?
-
 ?
beta-glycerophosphate + H2O
-
 Homo sapiens glycerol + phosphate
-
 ?
diphosphate + H2O
-
 Homo sapiens 2 phosphate
-
 ?
glucose 1-phosphate + H2O
-
 Homo sapiens glucose + phosphate
-
 ?
p-nitrophenyl phosphate + H2O
-
 Homo sapiens p-nitrophenol + phosphate
-
 ?
p-nitrophenyl phosphate + H2O
-
 Bos taurus p-nitrophenol + phosphate
-
 ?
phenyl phosphate + H2O
-
 Homo sapiens phenol + phosphate
-
 ?
phosphoethanolamine + H2O
-
 Homo sapiens phosphate + ethanolamine
-
 ?
phosphoserine + H2O
-
 Homo sapiens phosphate + Ser
-
 ?
triphosphate + H2O
-
 Homo sapiens diphosphate + phosphate
-
 ?
UDP + H2O
-
 Homo sapiens ?
-
 ?
UTP + H2O
-
 Homo sapiens ?
-
 ?

Turnover Number [1/s]

Turnover Number Minimum [1/s] Turnover Number Maximum [1/s] Substrate Comment Organism Structure
additional information
-
 additional information
-
 Homo sapiens
additional information
-
 additional information
-
 Bos taurus