Literature summary for 3.1.26.5 extracted from

Ueda, T.; Yamaguchi, H.; Miyanoshita, M.; Nakashima, T.; Kakuta, Y.; Kimura, M.
Characterization of the peripheral structures of archaeal RNase P RNA from Pyrococcus horikoshii OT3 (2014), J. Biochem., 155, 25-33.

Search for more literature for 3.1.26.5

Protein Variants

Protein Variants	Comment	Organism
additional information	in order to investigate their functional role, six mutants are propared, DELTAP1, DELTAP3, DELTAP8, DELTAP9, DELTAP12, and DELTAP15, in which the stem-loops including helices P1, P3, P8, P9, P12/12.1/12.2, and P15/16 are individually deleted respectively. the mutant proteins are characterized with respect to pre-tRNA cleavage activity in the presence of five proteins and also to the ability to form a complex with the proteins. The results indicate that elimination of the stem-loops results in a reduction of the pre-tRNA cleavage activity. It is further suggested that the stem-loops containing P3 or P15/16 form a binding site for the PhoPop5-PhoRpp30 complex, and that their interaction is closely involved in the structural formation of an active site in PhopRNA	Pyrococcus horikoshii

Organism

Organism	UniProt	Comment	Textmining
Pyrococcus horikoshii	-	-	-
Pyrococcus horikoshii OT-3	-	-	-

Synonyms

Synonyms	Comment	Organism
ribonuclease P	-	Pyrococcus horikoshii
RNase P	-	Pyrococcus horikoshii

Use of this online version of BRENDA is free under the CC BY 4.0 license. See terms of use for full details.

Release 2023.1 (January 2023)