Inhibitors | Comment | Organism | Structure |
---|---|---|---|
additional information | disruption of tertiary structure inhibits the enzyme | Trypanosoma brucei | |
puromycin | about 80% inhibition at 6 mM | Trypanosoma brucei |
Localization | Comment | Organism | GeneOntology No. | Textmining |
---|---|---|---|---|
mitochondrion | mtRNase P | Trypanosoma brucei | 5739 | - |
Metals/Ions | Comment | Organism | Structure |
---|---|---|---|
Mg2+ | - |
Trypanosoma brucei |
Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
---|---|---|---|
70000 | - |
gel filtration, mitochondrial enzyme form | Trypanosoma brucei |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
additional information | Trypanosoma brucei | regulation of gene expression can be achieved by creating a complex made of target mRNA and a complementary small oligonucleotide that resembels natural enzyme substrate | ? | - |
? | |
tRNA precursor + H2O | Trypanosoma brucei | cleavage of 5'-terminal oligonucleotide, maturation, essential | mature tRNA + 5'-oligonucleotide | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Trypanosoma brucei | - |
enzyme is not a RNA-dependent ribozyme, but may contain an RNA component | - |
Purification (Comment) | Organism |
---|---|
11675fold | Trypanosoma brucei |
Specific Activity Minimum [µmol/min/mg] | Specific Activity Maximum [µmol/min/mg] | Comment | Organism |
---|---|---|---|
additional information | - |
- |
Trypanosoma brucei |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
additional information | regulation of gene expression can be achieved by creating a complex made of target mRNA and a complementary small oligonucleotide that resembels natural enzyme substrate | Trypanosoma brucei | ? | - |
? | |
tRNA precursor + H2O | cleavage of 5'-terminal oligonucleotide, maturation, essential | Trypanosoma brucei | mature tRNA + 5'-oligonucleotide | - |
? | |
tRNA precursor + H2O | cleavage of 5'-terminal oligonucleotide | Trypanosoma brucei | mature tRNA + 5'-oligonucleotide | generates 5'-phosphate,3'-hydroxyl-product | ? |
Synonyms | Comment | Organism |
---|---|---|
RNase P | - |
Trypanosoma brucei |
Temperature Optimum [°C] | Temperature Optimum Maximum [°C] | Comment | Organism |
---|---|---|---|
28 | - |
assay at | Trypanosoma brucei |
pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
---|---|---|---|
7.4 | - |
assay at | Trypanosoma brucei |