Cloned (Comment) | Organism |
---|---|
gene for the protein moiety | Bacillus subtilis |
Inhibitors | Comment | Organism | Structure |
---|---|---|---|
tRNA | mature tRNA is a competitive inhibitor of pre-tRNA cleavage | Bacillus subtilis | |
tRNA | - |
Homo sapiens |
Localization | Comment | Organism | GeneOntology No. | Textmining |
---|---|---|---|---|
additional information | eukaryotic cells may contain multiple RNase P activities, a nucear type as well as enzyme species in mitochondria and chloroplasts | Homo sapiens | - |
- |
additional information | eukaryotic cells may contain multiple RNase P activities, a nucear type as well as enzyme species in mitochondria and chloroplasts | Saccharomyces cerevisiae | - |
- |
additional information | eukaryotic cells may contain multiple RNase P activities, a nucear type as well as enzyme species in mitochondria and chloroplasts | Xenopus laevis | - |
- |
additional information | eukaryotic cells may contain multiple RNase P activities, a nucear type as well as enzyme species in mitochondria and chloroplasts | Schizosaccharomyces pombe | - |
- |
nucleus | - |
Homo sapiens | 5634 | - |
nucleus | - |
Saccharomyces cerevisiae | 5634 | - |
nucleus | - |
Xenopus laevis | 5634 | - |
nucleus | - |
Schizosaccharomyces pombe | 5634 | - |
Metals/Ions | Comment | Organism | Structure |
---|---|---|---|
K+ | - |
Homo sapiens | |
K+ | - |
Schizosaccharomyces pombe | |
K+ | optimal activity at 0.3-1 M NH4Cl or KCl | Bacillus subtilis | |
Mg2+ | - |
Homo sapiens | |
Mg2+ | optimal activity at 20-200 mM MgCl2 | Bacillus subtilis | |
NH4+ | - |
Homo sapiens | |
NH4+ | optimal activity at 0.3-1 M NH4Cl or KCl | Bacillus subtilis |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
pre-tRNA + H2O | Homo sapiens | - |
tRNA + 5'-oligoribonucleotide | - |
? | |
pre-tRNA + H2O | Saccharomyces cerevisiae | - |
tRNA + 5'-oligoribonucleotide | - |
? | |
pre-tRNA + H2O | Bacillus subtilis | the enzyme is responsible for the cleavage of sequences from the 5' ends of precursors of tRNAs to produce the mature 5' terminus of the tRNA molecules | tRNA + 5'-oligoribonucleotide | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Bacillus subtilis | - |
- |
- |
Homo sapiens | - |
- |
- |
Saccharomyces cerevisiae | - |
- |
- |
Schizosaccharomyces pombe | - |
- |
- |
Xenopus laevis | - |
- |
- |
Posttranslational Modification | Comment | Organism |
---|---|---|
ribonucleoprotein | - |
Homo sapiens |
ribonucleoprotein | - |
Saccharomyces cerevisiae |
ribonucleoprotein | - |
Schizosaccharomyces pombe |
ribonucleoprotein | the enzyme requires an RNA as well as a protein subunit for its in vivo activity | Bacillus subtilis |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
HeLa cell | - |
Homo sapiens | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
pre-tRNA + H2O | - |
Homo sapiens | tRNA + 5'-oligoribonucleotide | - |
? | |
pre-tRNA + H2O | - |
Saccharomyces cerevisiae | tRNA + 5'-oligoribonucleotide | - |
? | |
pre-tRNA + H2O | the enzyme is responsible for the cleavage of sequences from the 5' ends of precursors of tRNAs to produce the mature 5' terminus of the tRNA molecules | Bacillus subtilis | tRNA + 5'-oligoribonucleotide | - |
? | |
pre-tRNA precursor + H2O | - |
Homo sapiens | tRNA + 5'-oligoribonucleotide | - |
? | |
pre-tRNA precursor + H2O | - |
Saccharomyces cerevisiae | tRNA + 5'-oligoribonucleotide | - |
? | |
pre-tRNA precursor + H2O | - |
Xenopus laevis | tRNA + 5'-oligoribonucleotide | - |
? | |
pre-tRNA precursor + H2O | - |
Schizosaccharomyces pombe | tRNA + 5'-oligoribonucleotide | - |
? | |
pre-tRNA precursor + H2O | the conserved sequences CCA and GUUCG, as well as the substrate bond, occur on the same face of the coaxial helix that constitutes the minimum substrate for the enzyme | Bacillus subtilis | tRNA + 5'-oligoribonucleotide | - |
? |