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Literature summary for 3.1.26.4 extracted from

  • Bigot, A.; Raynaud, C.; Dubail, I.; Dupuis, M.; Hossain, H.; Hain, T.; Chakraborty, T.; Charbit, A.
    lmo1273, a novel gene involved in Listeria monocytogenes virulence (2009), Microbiology, 155, 891-902.
    View publication on PubMed

Protein Variants

Protein Variants Comment Organism
additional information lmo1273 can complement an Escherichia coli rnhA-rnhB thermosensitive growth phenotype, suggesting that it encodes a functional RNase H. DELTAlmo1273: Chromosomal deletion mutant. Inactivation of lmo1273 provokes a strong attenuation of virulence in the mouse model, and kinetic studies in infected mice reveals that multiplication of the lmo1273 mutant in target organs is significantly impaired. DELTAlmo1272/DELTA1273 double mutant. MIC2067-lmo1273 using the Escherichia coli strain MIC2067 (an rnhA-rnhB double mutant strain) and transformed it with plasmid pTrc99A-lmo1273, carrying the lmo1273 gene under IPTG-inducible promoter control Listeria monocytogenes EGD-e

Organism

Organism UniProt Comment Textmining
Listeria monocytogenes EGD-e Q8Y7K4
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Synonyms

Synonyms Comment Organism
lmo1273
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Listeria monocytogenes EGD-e
RNase H
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Listeria monocytogenes EGD-e
RNase HII
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Listeria monocytogenes EGD-e