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Literature summary for 3.1.26.3 extracted from

  • Ben-Artzi, H.; Zeelon, E.; Gorecki, M.; Panet, A.
    Double-stranded RNA-dependent RNase activity associated with human immunodeficiency virus type 1 reverse transcriptase (1992), Proc. Natl. Acad. Sci. USA, 89, 927-931.
    View publication on PubMedView publication on EuropePMC

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
double-stranded RNA + H2O Homo sapiens cleaves multimeric tRNA precursor at the spacer region, also involved in processing of precursor rRNA, hnRNA and early T7-mRNA. Also cleaves double-stranded DNA and single-stranded RNA 5'-phosphooligonucleotides
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Organism

Organism UniProt Comment Textmining
Homo sapiens
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Purification (Commentary)

Purification (Comment) Organism
of the human immunodeficiency virus type 1 reverse transcriptase Homo sapiens

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
double-stranded RNA + H2O reverse transcriptase of HIV-1 possesses RNase D activity Homo sapiens 5'-phosphooligonucleotides
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double-stranded RNA + H2O cleaves multimeric tRNA precursor at the spacer region, also involved in processing of precursor rRNA, hnRNA and early T7-mRNA. Also cleaves double-stranded DNA and single-stranded RNA Homo sapiens 5'-phosphooligonucleotides
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Synonyms

Synonyms Comment Organism
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