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Literature summary for 3.1.26.13 extracted from
- Altered error specificity of RNase H-deficient HIV-1 reverse transcriptases during DNA-dependent DNA synthesis (2013), Nucleic Acids Res., 41, 4601-4612.
Cloned(Commentary)
| Cloned (Comment) | Organism |
|---|---|
| expressed in Escherichia coli XL1 Blue cells | Human immunodeficiency virus 1 |
Natural Substrates/ Products (Substrates)
| Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| RNA-DNA duplex + H2O | Human immunodeficiency virus 1 | - |
? | - |
? |  |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Human immunodeficiency virus 1 | - |
- |
- |
Purification (Commentary)
| Purification (Comment) | Organism |
|---|---|
| Ni-NTA agarose column chromatography | Human immunodeficiency virus 1 |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| RNA-DNA duplex + H2O | - |
Human immunodeficiency virus 1 | ? | - |
? | |
Synonyms
| Synonyms | Comment | Organism |
|---|---|---|
| reverse transcriptase | the large subunit of reverse transcriptase contains separated DNA polymerase and RNase H domains at its N- and C-terminal regions, respectively | Human immunodeficiency virus 1 |
| ribonuclease H | - |
Human immunodeficiency virus 1 |
| RNase H | - |
Human immunodeficiency virus 1 |
General Information
| General Information | Comment | Organism |
|---|---|---|
| malfunction | RNase H-deficient HIV-1 reverse transcriptase shows altered error specificity during DNA-dependent DNA synthesis | Human immunodeficiency virus 1 |
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