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Literature summary for 3.1.26.13 extracted from

  • Gabbara, S.; Davis, W.R.; Hupe, L.; Hupe, D.; Peliska, J.A.
    Inhibitors of DNA strand transfer reactions catalyzed by HIV-1 reverse transcriptase (1999), Biochemistry, 38, 13070-13076.
    View publication on PubMed

Inhibitors

Inhibitors Comment Organism Structure
[2-(4-chlorophenyl)hydrazinylidene]propanedioic acid additionally inhibits DNA strand transfer and DNA polymerase activity of the retroviral reverse transcriptase Human immunodeficiency virus 1

Organism

Organism UniProt Comment Textmining
Human immunodeficiency virus 1
-
-
-

Synonyms

Synonyms Comment Organism
RNase H
-
Human immunodeficiency virus 1

IC50 Value

IC50 Value IC50 Value Maximum Comment Organism Inhibitor Structure
0.003
-
pH 7.6, 37°C Human immunodeficiency virus 1 [2-(4-chlorophenyl)hydrazinylidene]propanedioic acid