Literature summary for 3.1.26.13 extracted from

Peliska, J.A.; Balasubramanian, S.; Giedroc, D.P.; Benkovic, S.J.
Recombinant HIV-1 nucleocapsid protein accelerates HIV-1 reverse transcriptase catalyzed DNA strand transfer reactions and modulates RNase H activity (1994), Biochemistry, 33, 13817-13823.

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Activating Compound

Activating Compound	Comment	Organism	Structure
nucleocapsid protein NCp7	enhances ribonuclease H activity and changes the specificity of hydrolysis. As a model, the NCp7 binds to the DNA strand and through interaction with HIV-1 RT facilitates the delivery of the DNA-RNA duplex into the RNase H site for cleavage, thereby altering the rate and location of RNase H cleavage	Human immunodeficiency virus 1

Organism

Organism	UniProt	Comment	Textmining
Human immunodeficiency virus 1	-	-	-

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Release 2023.1 (January 2023)