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Literature summary for 3.1.26.11 extracted from

  • Levinger, L.; Serjanov, D.
    Pathogenesis-related mutations in the T-loops of human mitochondrial tRNAs affect 3' end processing and tRNA structure (2012), RNA Biol., 9, 283-291.
    View publication on PubMedView publication on EuropePMC
Search for more literature for 3.1.26.11

Cloned(Commentary)

Cloned (Comment) Organism
expressed in a baculovirus-infection system Homo sapiens

KM Value [mM]

KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
0.000018
-
 pre-tRNAHis 25 mM K-MOPS, 2 mM MgCl2, at pH 6.8 and 37°C Homo sapiens
0.000024
-
 pre-tRNALeu(UUR) 25 mM K-MOPS, 3 mM CaCl2, at pH 6.8 and 37°C Homo sapiens
0.000029
-
 pre-tRNAGly 25 mM K-MOPS, 2 mM MgCl2, at pH 6.8 and 37°C Homo sapiens
0.000048
-
 pre-tRNAIle 25 mM K-MOPS, 2 mM MgCl2, at pH 6.8 and 37°C Homo sapiens

Localization

Localization Comment Organism GeneOntology No. Textmining
mitochondrion
-
 Homo sapiens 5739
-

Organism

Organism UniProt Comment Textmining
Homo sapiens
-
-
-

Purification (Commentary)

Purification (Comment) Organism
-
 Homo sapiens

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
pre-tRNACys + H2O
-
 Homo sapiens ?
-
 ?
pre-tRNAGlu + H2O
-
 Homo sapiens ?
-
 ?
pre-tRNAGly + H2O
-
 Homo sapiens ?
-
 ?
pre-tRNAHis + H2O
-
 Homo sapiens ?
-
 ?
pre-tRNAIle + H2O
-
 Homo sapiens ?
-
 ?
pre-tRNALeu(CUN) + H2O
-
 Homo sapiens ?
-
 ?
pre-tRNALeu(UUR) + H2O
-
 Homo sapiens ?
-
 ?
pre-tRNALys + H2O
-
 Homo sapiens ?
-
 ?
pre-tRNASer(AGY) + H2O
-
 Homo sapiens ?
-
 ?
pre-tRNAThr + H2O
-
 Homo sapiens ?
-
 ?
pre-tRNATyr + H2O
-
 Homo sapiens ?
-
 ?

Synonyms

Synonyms Comment Organism
tRNase ZL long isoform Homo sapiens

Turnover Number [1/s]

Turnover Number Minimum [1/s] Turnover Number Maximum [1/s] Substrate Comment Organism Structure
0.018
-
 pre-tRNAIle 25 mM K-MOPS, 2 mM MgCl2, at pH 6.8 and 37°C Homo sapiens
0.035
-
 pre-tRNAGly 25 mM K-MOPS, 2 mM MgCl2, at pH 6.8 and 37°C Homo sapiens
0.237
-
 pre-tRNAHis 25 mM K-MOPS, 2 mM MgCl2, at pH 6.8 and 37°C Homo sapiens
0.25
-
 pre-tRNALeu(UUR) 25 mM K-MOPS, 3 mM CaCl2, at pH 6.8 and 37°C Homo sapiens

kcat/KM [mM/s]

kcat/KM Value [1/mMs-1] kcat/KM Value Maximum [1/mMs-1] Substrate Comment Organism Structure
417
-
 pre-tRNAIle 25 mM K-MOPS, 2 mM MgCl2, at pH 6.8 and 37°C Homo sapiens
1233
-
 pre-tRNAGly 25 mM K-MOPS, 2 mM MgCl2, at pH 6.8 and 37°C Homo sapiens
12670
-
 pre-tRNAHis 25 mM K-MOPS, 2 mM MgCl2, at pH 6.8 and 37°C Homo sapiens
15500
-
 pre-tRNALeu(UUR) 25 mM K-MOPS, 3 mM CaCl2, at pH 6.8 and 37°C Homo sapiens