Any feedback?
Literature summary for 3.1.21.B1 extracted from
- EndoQ and EndoV work individually for damaged DNA base repair in Pyrococcus furiosus (2015), Biochimie, 118, 264-269.
Cloned(Commentary)
| Cloned (Comment) | Organism |
|---|---|
| overexpression in Escherichia coli | Pyrococcus furiosus |
Molecular Weight [Da]
| Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
|---|---|---|---|
| 47653 | - |
x * 47653, calculated from sequence | Pyrococcus furiosus |
Natural Substrates/ Products (Substrates)
| Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| deoxyinosine-containing deoxyoligonucleotide + H2O | Pyrococcus furiosus | the enzyme is involved in damaged DNA repair | ? | - |
? |  |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Pyrococcus furiosus | Q8U0N5 | - |
- |
Purification (Commentary)
| Purification (Comment) | Organism |
|---|---|
- |
Pyrococcus furiosus |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| deoxyinosine-containing deoxyoligonucleotide + H2O | the enzyme is involved in damaged DNA repair | Pyrococcus furiosus | ? | - |
? | |
| deoxyinosine-containing deoxyoligonucleotide + H2O | endonucleolytic cleavage of the phosphodiester bond 5' from deoxyinosine | Pyrococcus furiosus | ? | - |
? | |
Subunits
| Subunits | Comment | Organism |
|---|---|---|
| ? | x * 47653, calculated from sequence | Pyrococcus furiosus |
Synonyms
| Synonyms | Comment | Organism |
|---|---|---|
| EndoQ | - |
Pyrococcus furiosus |
| PF1551 | locus name | Pyrococcus furiosus |
| PfuEndoQ | - |
Pyrococcus furiosus |
Temperature Optimum [°C]
| Temperature Optimum [°C] | Temperature Optimum Maximum [°C] | Comment | Organism |
|---|---|---|---|
| 75 | - |
- |
Pyrococcus furiosus |
Temperature Range [°C]
| Temperature Minimum [°C] | Temperature Maximum [°C] | Comment | Organism |
|---|---|---|---|
| 70 | 80 | 70°C: about 50% of maximal activity, 80°C: about 35% of maximal activity | Pyrococcus furiosus |
pH Optimum
| pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
|---|---|---|---|
| 9.5 | - |
- |
Pyrococcus furiosus |
pH Range
| pH Minimum | pH Maximum | Comment | Organism |
|---|---|---|---|
| 8.5 | 9.5 | pH 8.5: about 60% of maximal activity, pH 9.5: optimum, pH 10.0: less than 19% of maximal activity | Pyrococcus furiosus |
pI Value
| Organism | Comment | pI Value Maximum | pI Value |
|---|---|---|---|
| Pyrococcus furiosus | calculated from sequence | - |
8.1 |
General Information
| General Information | Comment | Organism |
|---|---|---|
| physiological function | the enzyme is involved in damaged DNA repair. EndoQ predominately functions over EndoV (EC 3.1.21.7) to start the process of damaged base repair in Pyrococcus furiosus cells | Pyrococcus furiosus |
Use of this online version of BRENDA is free under the CC BY 4.0 license. See terms of use for full details.
Release 2023.1 (January 2023)
Legal
Curated at
Member of
