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Literature summary for 3.1.21.9 extracted from

  • Carlson, K.; Overvatn, A.
    Bacteriophage T4 endonucleases II and IV, oppositely affected by dCMP hydroxymethylase activity, have different roles in the degradation and in the RNA polymerase-dependent replication of T4 cytosine-containing DNA (1986), Genetics, 114, 669-685.
    View publication on PubMedView publication on EuropePMC

Activating Compound

Activating Compound Comment Organism Structure
additional information activity of endonuclease IV is stimulated in the presence of a wild-type dCMP hydroxymethylase Tequatrovirus T4

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
DNA where cytosine is partially or completely replaced by hydroxymethylcytosine + H2O Tequatrovirus T4 DNA where cytosine is partially or completely replaced by hydroxymethylcytosine is degraded in vivo by T4 endonuclease II, EC 3.1.21.8, and endonuclease IV, EC 3.1.21.9 ?
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Organism

Organism UniProt Comment Textmining
Tequatrovirus T4
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-
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
DNA where cytosine is partially or completely replaced by hydroxymethylcytosine + H2O DNA where cytosine is partially or completely replaced by hydroxymethylcytosine is degraded in vivo by T4 endonuclease II, EC 3.1.21.8, and endonuclease IV, EC 3.1.21.9 Tequatrovirus T4 ?
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?

Synonyms

Synonyms Comment Organism
endonuclease IV
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Tequatrovirus T4