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Literature summary for 3.1.21.8 extracted from

  • Lagerbaeck, P.; Andersson, E.; Malmberg, C.; Carlson, K.
    Bacteriophage T4 endonuclease II, a promiscuous GIY-YIG nuclease, binds as a tetramer to two DNA substrates (2009), Nucleic Acids Res., 37, 6174-6183.
    View publication on PubMedView publication on EuropePMC

Protein Variants

Protein Variants Comment Organism
E118A mutation in a putatively catalytic residue. Mutant E118A is able to bind stably as monomer or dimer to a single substrate. In low-salt conditions, mutant is present as dimer in solution Tequatrovirus T4
G49A in low-salt conditions, mutant is present as dimer in solution Tequatrovirus T4
R57A in low-salt conditions, mutant is present as dimer in solution Tequatrovirus T4

Organism

Organism UniProt Comment Textmining
Tequatrovirus T4 P07059
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