Cloned (Comment) | Organism |
---|---|
expressed in Escherichia coli BL21-Codon Plus (DE3)-RIPL cells | Homo sapiens |
Protein Variants | Comment | Organism |
---|---|---|
Y91A | the mutant has lost its affinity for branched DNA substrates | Homo sapiens |
Localization | Comment | Organism | GeneOntology No. | Textmining |
---|---|---|---|---|
cytoplasm | - |
Homo sapiens | 5737 | - |
nucleolus | - |
Homo sapiens | 5730 | - |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
additional information | Homo sapiens | the enzyme shows affinity for but does not cleave branched DNA substrates like 5'-flap, 3'-flap, pseudo-Y, fork, 3-way junction, and Holliday junction | ? | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Homo sapiens | Q8N8Q3 | - |
- |
Purification (Comment) | Organism |
---|---|
Ni-NTA column chromatography and Superdex 75 gel filtration | Homo sapiens |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
colon | - |
Homo sapiens | - |
fibroblast | - |
Homo sapiens | - |
kidney | - |
Homo sapiens | - |
liver | - |
Homo sapiens | - |
lung | - |
Homo sapiens | - |
ovary | - |
Homo sapiens | - |
pancreas | - |
Homo sapiens | - |
prostate gland | - |
Homo sapiens | - |
stomach | - |
Homo sapiens | - |
testis | highest expression | Homo sapiens | - |
urinary bladder | - |
Homo sapiens | - |
uterine cervix | - |
Homo sapiens | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
additional information | the enzyme shows affinity for but does not cleave branched DNA substrates like 5'-flap, 3'-flap, pseudo-Y, fork, 3-way junction, and Holliday junction | Homo sapiens | ? | - |
? |
Synonyms | Comment | Organism |
---|---|---|
endonuclease V | - |
Homo sapiens |
EndoV | - |
Homo sapiens |