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Literature summary for 3.1.21.7 extracted from
- T4 endonuclease V: review and application to dermatology (2008), Expert. Opin. Biol. Ther., 8, 829-838.
Application
| Application | Comment | Organism |
|---|---|---|
| medicine | in xeroderma pigmentosum patients, topical application of liposome-encapsulated T4 endonuclease V reduces the incidence of basal cell carcinomas by 30% and of actinic keratoses by more than 68% | Tequatrovirus T4 |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Tequatrovirus T4 | - |
- |
- |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| DNA + H2O | endonuclease V repairs UV-induced cyclobutane pyrimidine dimers in DNA | Tequatrovirus T4 | 5'-phosphoryltermini DNA + 3'-hydroxyltermini DNA | - |
? |  |
| double-stranded plasmid DNA + H2O | - |
Tequatrovirus T4 | nicked circular DNA + linearized DNA | - |
? | |
Synonyms
| Synonyms | Comment | Organism |
|---|---|---|
| endonuclease V | - |
Tequatrovirus T4 |
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Release 2023.1 (January 2023)
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