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Literature summary for 3.1.21.7 extracted from

  • Doi, Y.; Katafuchi, A.; Fujiwara, Y.; Hitomi, K.; Tainer, J.A.; Ide, H.; Iwai, S.
    Synthesis and characterization of oligonucleotides containing 2'-fluorinated thymidine glycol as inhibitors of the endonuclease III reaction (2006), Nucleic Acids Res., 34, 1540-1551.
    View publication on PubMedView publication on EuropePMC

Inhibitors

Inhibitors Comment Organism Structure
additional information an oligonucleotide duplex containing a 2'-fluorinated sugar moiety at the cyclobutane pyrimidine dimer (CPD) site inhibits the T4 Endo V reaction by stabilizing the covalent enzyme-DNA complex Tequatrovirus T4

Organism

Organism UniProt Comment Textmining
Tequatrovirus T4
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-
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
34-mer oligonucleotide + H2O oligonucleotide duplex containing a fluorine atom at the 2' position of the 5' component of the cyclobutane pyrimidine dimer Tequatrovirus T4 fragments of 34mer-oligonucleotide
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?

Synonyms

Synonyms Comment Organism
T4 endonuclease V
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Tequatrovirus T4