Any feedback?
Please rate this page
(literature.php)
(0/150)

BRENDA support

Literature summary for 3.1.21.7 extracted from

  • Morikawa, K.; Matsumoto, O.; Tsujimoto, M.; Katayanagi, K.; Ariyoshi, M.; Doi, T.; Ikehara, M.; Inaoka, T.; Ohtsuka, E.
    X-ray structure of T4 endonuclease V: An excision repair enzyme specific for a pyrimidine dimer (1992), Science, 256, 523-526.
    View publication on PubMed
Search for more literature for 3.1.21.7

Crystallization (Commentary)

Crystallization (Comment) Organism
2.5 A resolution Tequatrovirus T4

Protein Variants

Protein Variants Comment Organism
E23Q retains ability to bind the substrate Tequatrovirus T4
R3Q greatly decreased DNA binding ability Tequatrovirus T4

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
DNA + H2O Tequatrovirus T4 pyrimidine dimer-specific 5'-phosphoryltermini DNA + 3'-hydroxyltermini DNA
-
 ?
DNA + H2O Tequatrovirus T4 two distinct activities: pyrimidine dimer glycosylase and apurinic-apyrimidinic endonuclease, beta-elimination of the 3'-phosphate of an abasic site 5'-phosphoryltermini DNA + 3'-hydroxyltermini DNA
-
 ?
double-stranded plasmid DNA + H2O Tequatrovirus T4
-
 nicked circular DNA + linearized DNA
-
 ?

Organism

Organism UniProt Comment Textmining
Tequatrovirus T4
-
-
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
DNA + H2O pyrimidine dimer-specific Tequatrovirus T4 5'-phosphoryltermini DNA + 3'-hydroxyltermini DNA
-
 ?
DNA + H2O two distinct activities: pyrimidine dimer glycosylase and apurinic-apyrimidinic endonuclease, beta-elimination of the 3'-phosphate of an abasic site Tequatrovirus T4 5'-phosphoryltermini DNA + 3'-hydroxyltermini DNA
-
 ?
double-stranded plasmid DNA + H2O
-
 Tequatrovirus T4 nicked circular DNA + linearized DNA
-
 ?