Any feedback?
Please rate this page
(literature.php)
(0/150)

BRENDA support

Literature summary for 3.1.21.1 extracted from

  • Napirei, M.; Wulf, S.; Eulitz, D.; Mannherz, H.G.; Kloeckl, T.
    Comparative characterization of rat deoxyribonuclease 1 (Dnase1) and murine deoxyribonuclease 1-like 3 (Dnase1l3) (2005), Biochem. J., 389, 355-364.
    View publication on PubMedView publication on EuropePMC
Search for more literature for 3.1.21.1

Cloned(Commentary)

Cloned (Comment) Organism
expression in NIH-3T3 fibroblasts Mus musculus
expression in NIH-3T3 fibroblasts Rattus norvegicus

Inhibitors

Inhibitors Comment Organism Structure
EDTA
-
 Mus musculus
EDTA
-
 Rattus norvegicus
EGTA
-
 Mus musculus
EGTA
-
 Rattus norvegicus
G-actin
-
 Rattus norvegicus
heparin
-
 Mus musculus
Zn2+
-
 Mus musculus
Zn2+
-
 Rattus norvegicus

Localization

Localization Comment Organism GeneOntology No. Textmining
endoplasmic reticulum
-
 Mus musculus 5783
-
endoplasmic reticulum
-
 Rattus norvegicus 5783
-

Metals/Ions

Metals/Ions Comment Organism Structure
Ca2+ required Mus musculus
Ca2+ required Rattus norvegicus
Mg2+ either Mg2+ or Mn2+ is required in addition to Ca2+ Mus musculus
Mg2+ either Mg2+ or Mn2+ is required in addition to Ca2+ Rattus norvegicus
Mn2+ either Mg2+ or Mn2+ is required in addition to Ca2+ Mus musculus
Mn2+ either Mg2+ or Mn2+ is required in addition to Ca2+ Rattus norvegicus

Organism

Organism UniProt Comment Textmining
Mus musculus
-
-
-
Rattus norvegicus P21704
-
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
double-stranded DNA + H2O high activity on plasmid DNA, weak activity on nuclear DNA Rattus norvegicus 5'-phosphooligonucleotides + ?
-
 ?
double-stranded DNA + H2O low activity on plasmid DNA, high activity on nuclear DNA Mus musculus 5'-phosphooligonucleotides + ?
-
 ?

Synonyms

Synonyms Comment Organism
deoxyribonuclease 1
-
 Rattus norvegicus
deoxyribonuclease 1-like 3
-
 Mus musculus
Dnase1
-
 Rattus norvegicus