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Literature summary for 3.1.2.4 extracted from

  • Hawes, J.W.; Jaskiewicz, J.; Shimomura, Y.; Huang, B.; Bunting, J.; Harper, E.T.; Harris, R.A.
    Primary structure and tissue-specific expression of human beta-hydroxyisobutyryl-coenzyme A hydrolase (1996), J. Biol. Chem., 271, 26430-26434.
    View publication on PubMed

Cloned(Commentary)

Cloned (Comment) Organism
expression in Escherichia coli Homo sapiens

Molecular Weight [Da]

Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
36000
-
x * 36000, SDS-PAGE Homo sapiens
39398
-
x * 39398, calculation from nucleotide sequence Homo sapiens

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
3-hydroxy-2-methylpropanoyl-CoA + H2O Rattus norvegicus
-
?
-
?
3-hydroxy-2-methylpropanoyl-CoA + H2O Homo sapiens the enzyme is responsible for the specific hydrolysis of 3-hydroxy-2-methylpropanoyl-CoA, a saline catabolite ?
-
?
3-hydroxypropanoyl-CoA + H2O Homo sapiens hydrolysis of beta-hydroxypropionyl-CoA, an intermediate in a minor pathway of propionate metabolism CoA + 3-hydroxypropanoate
-
?

Organism

Organism UniProt Comment Textmining
Homo sapiens Q6NVY1
-
-
Rattus norvegicus
-
-
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
3-hydroxy-2-methylpropanoyl-CoA + H2O
-
Rattus norvegicus CoA + 3-hydroxy-2-methylpropanoate
-
?
3-hydroxy-2-methylpropanoyl-CoA + H2O
-
Homo sapiens CoA + 3-hydroxy-2-methylpropanoate
-
?
3-hydroxy-2-methylpropanoyl-CoA + H2O
-
Rattus norvegicus ?
-
?
3-hydroxy-2-methylpropanoyl-CoA + H2O the enzyme is responsible for the specific hydrolysis of 3-hydroxy-2-methylpropanoyl-CoA, a saline catabolite Homo sapiens ?
-
?
3-hydroxypropanoyl-CoA + H2O
-
Rattus norvegicus CoA + 3-hydroxypropanoate
-
?
3-hydroxypropanoyl-CoA + H2O
-
Homo sapiens CoA + 3-hydroxypropanoate
-
?
3-hydroxypropanoyl-CoA + H2O hydrolysis of beta-hydroxypropionyl-CoA, an intermediate in a minor pathway of propionate metabolism Homo sapiens CoA + 3-hydroxypropanoate
-
?

Subunits

Subunits Comment Organism
? x * 36000, SDS-PAGE Homo sapiens
? x * 39398, calculation from nucleotide sequence Homo sapiens

Synonyms

Synonyms Comment Organism
beta-hydroxyisobutyryl-coenzyme A hydrolase
-
Homo sapiens
HIBYL-CoA hydrolase
-
Rattus norvegicus