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Literature summary for 3.1.2.23 extracted from

  • Li, Z.; Song, F.; Zhuang, Z.; Dunaway-Mariano, D.; Anderson, K.S.
    Monitoring enzyme catalysis in the multimeric state: direct observation of Arthrobacter 4-hydroxybenzoyl-coenzyme A thioesterase catalytic complexes using time-resolved electrospray ionization mass spectrometry (2009), Anal. Biochem., 394, 209-216.
    View publication on PubMedView publication on EuropePMC
Search for more literature for 3.1.2.23

Organism

Organism UniProt Comment Textmining
Arthrobacter sp.
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-
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Arthrobacter sp. SU / DSM 20407
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-
-

Purification (Commentary)

Purification (Comment) Organism
-
 Arthrobacter sp.

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
4-Hydroxybenzoyl-CoA + H2O the CoA pantothenic acid moiety is inserted into the outer part of the active site tunnel and the nucleotide moiety is anchored to the protein surface, whereas the hydroxybenzoyl group binds in an enclosed pocket. Product 4-hydroxybenzoate is released from the active site of the enzyme prior to the release of product CoA following catalytic turnover. 4-Hydroxybenzoate dissociates directly from the hydroxybenzoyl binding pocket more quickly than CoA can move out of the connecting tunnel Arthrobacter sp. 4-Hydroxybenzoate + CoA
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 ?
4-Hydroxybenzoyl-CoA + H2O the CoA pantothenic acid moiety is inserted into the outer part of the active site tunnel and the nucleotide moiety is anchored to the protein surface, whereas the hydroxybenzoyl group binds in an enclosed pocket. Product 4-hydroxybenzoate is released from the active site of the enzyme prior to the release of product CoA following catalytic turnover. 4-Hydroxybenzoate dissociates directly from the hydroxybenzoyl binding pocket more quickly than CoA can move out of the connecting tunnel Arthrobacter sp. SU / DSM 20407 4-Hydroxybenzoate + CoA
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 ?

Subunits

Subunits Comment Organism
tetramer mass spectrometry Arthrobacter sp.

Synonyms

Synonyms Comment Organism
4-HBA-CoA thioesterase
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 Arthrobacter sp.
4-hydroxybenzoyl-coenzyme A thioesterase
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 Arthrobacter sp.