Localization | Comment | Organism | GeneOntology No. | Textmining |
---|---|---|---|---|
axon | preferably targeted to in mature neurons | Mus musculus | 30424 | - |
synaptic vesicle | - |
Mus musculus | 8021 | - |
synaptosome | - |
Mus musculus | - |
- |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
additional information | Mus musculus | PPT1 deficiency causes progressive neurological disorder infantile neuronal ceroid lipofuscinosis, only in neurons of the cerebral and cerbellar cortexes and retina not in other cell types, characterized by early loss of vision and massiv neuronal death | ? | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Mus musculus | - |
PPT1 | - |
Reaction | Comment | Organism | Reaction ID |
---|---|---|---|
palmitoyl[protein] + H2O = palmitate + protein | specific for long-chain thioesters of fatty acids from S-acylated residues in proteins, palmitoyl cysteine and palmitoyl-CoA | Mus musculus |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
embryo | - |
Mus musculus | - |
epithelium | retinal | Mus musculus | - |
eye | - |
Mus musculus | - |
additional information | activity is increased during neuronal maturation | Mus musculus | - |
neuron | hippocampal, retinal, and cortical neurons | Mus musculus | - |
retina | - |
Mus musculus | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
4-methylumbelliferyl 6-S-palmitoyl-6-thio-beta-D-glucoside + H2O | artificial substrate | Mus musculus | 4-methylumbelliferyl 6-thio-beta-D-glucoside + palmitate | - |
? | |
additional information | PPT1 deficiency causes progressive neurological disorder infantile neuronal ceroid lipofuscinosis, only in neurons of the cerebral and cerbellar cortexes and retina not in other cell types, characterized by early loss of vision and massiv neuronal death | Mus musculus | ? | - |
? |
Synonyms | Comment | Organism |
---|---|---|
palmitoyl protein thioesterase 1 | - |
Mus musculus |
PPT1 | - |
Mus musculus |