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Literature summary for 3.1.2.1 extracted from

  • Buu, L.M.; Chen, Y.C.; Lee, F.J.
    Functional characterization and localization of acetyl-CoA hydrolase, Ach1p, in Saccharomyces cerevisiae (2003), J. Biol. Chem., 278, 17203-17209.
    View publication on PubMed
Search for more literature for 3.1.2.1

Protein Variants

Protein Variants Comment Organism
G277S/G279S mutant enzyme shows less than 5% of the activity of the wild-type enzyme Saccharomyces cerevisiae
G393E/G395S mutant enzyme shows less than 5% of the activity of the wild-type enzyme Saccharomyces cerevisiae

Localization

Localization Comment Organism GeneOntology No. Textmining
cytoplasm most of the Ach1p activity is distributed with mitochondria and little in the cytoplasm Saccharomyces cerevisiae 5737
-
mitochondrion most of the Ach1p activity is distributed with mitochondria and little in the cytoplasm Saccharomyces cerevisiae 5739
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Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
acetyl-CoA + H2O Saccharomyces cerevisiae Ach1p may be involved in a novel acetyl-CoA biogenesis and/or acetate utilization in mitochondria and thereby indirectly affect pseudohyphal development in yeast. Not involved in mitochondrial biogenesis CoA + acetate
-
 ?

Organism

Organism UniProt Comment Textmining
Saccharomyces cerevisiae
-
-
-

Purification (Commentary)

Purification (Comment) Organism
recombinant enzyme Saccharomyces cerevisiae

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
acetyl-CoA + H2O Ach1p may be involved in a novel acetyl-CoA biogenesis and/or acetate utilization in mitochondria and thereby indirectly affect pseudohyphal development in yeast. Not involved in mitochondrial biogenesis Saccharomyces cerevisiae CoA + acetate
-
 ?

Synonyms

Synonyms Comment Organism
Ach1p
-
 Saccharomyces cerevisiae