Literature summary for 3.1.16.1 extracted from

Gao, H.; Liu, Y.; Rumley, M.; Yuan, H.; Mao, B.
Sequence confirmation of chemically modified RNAs using exonuclease digestion and matrix-assisted laser desorption/ionization time-of-flight mass spectrometry (2009), Rapid Commun. Mass Spectrom., 23, 3423-3430.

Search for more literature for 3.1.16.1

Application

Application	Comment	Organism
analysis	broadly applicable, robust, and rapid method for complete sequence confirmation of highly modified oligonucleotides containing a mixture of 2'-deoxy, 2'-fluoro, 2'-O-methyl, abasic and ribonucleotides. The sense and antisense strands from synthetic short interfering RNA duplexes are digested individually using both 5'- and 3'-exonucleases and the resulting ladders are analyzed using MALDITOF mass spectrometry. Complete sequence confirmation for the antisense strands of four synthetic RNA duplexes is obtained, whereas a three-base sequence gap in the 5'-end is observed for all four sense strands. Outline of a general strategy for routine sequence confirmation of highly modified oligonucleotides	Bos taurus

Organism

Organism	UniProt	Comment	Textmining
Bos taurus	-	-	-

Source Tissue

Source Tissue	Comment	Organism	Textmining
commercial preparation	-	Bos taurus	-

Synonyms

Synonyms	Comment	Organism
BSP	-	Bos taurus

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Release 2023.1 (January 2023)