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BRENDA support

Literature summary for 3.1.13.4 extracted from

  • Rowlett, R.M.; Chrestensen, C.A.; Schroeder, M.J.; Harp, M.G.; Pelo, J.W.; Shabanowitz, J.; DeRose, R.; Hunt, D.F.; Sturgill, T.W.; Worthington, M.T.
    Inhibition of tristetraprolin deadenylation by poly(A) binding protein (2008), Am. J. Physiol. Gastrointest. Liver Physiol., 295, G421-G430.
    View publication on PubMedView publication on EuropePMC

Inhibitors

Inhibitors Comment Organism Structure
neomycin antibiotic neomycin B inhibits approximately 80% of PARN activity at a concentration of 10 microg/ml Mus musculus

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
additional information Mus musculus PARN protein levels are not appreciably altered by lipopolysaccharide stimulation in RAW264.7 macrophage cells ?
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?

Organism

Organism UniProt Comment Textmining
Mus musculus
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-
-

Source Tissue

Source Tissue Comment Organism Textmining
RAW-264.7 cell mouse macrophage cell line Mus musculus
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Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
additional information PARN protein levels are not appreciably altered by lipopolysaccharide stimulation in RAW264.7 macrophage cells Mus musculus ?
-
?

Synonyms

Synonyms Comment Organism
deadenylase
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Mus musculus
PARN
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Mus musculus
poly(A) ribonuclease
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Mus musculus