Any feedback?
Please rate this page
(literature.php)
(0/150)

BRENDA support

Literature summary for 3.1.13.4 extracted from

  • Korner, C.G.; Wormington, M.; Muckenthaler, M.; Schneider, S.; Dehlin, E.; Wahle, E.
    The deadenylating nuclease (DAN) is involved in poly(A) tail removal during the meiotic maturation of Xenopus oocytes (1998), EMBO J., 17, 5427-5437.
    View publication on PubMedView publication on EuropePMC
Search for more literature for 3.1.13.4

Activating Compound

Activating Compound Comment Organism Structure
CH3COOK absolute required in absence of spermidine Bos taurus
CH3COOK absolute required in absence of spermidine Xenopus sp.
spermidine absolute required in absence of salt Bos taurus
spermidine absolute required in absence of salt Xenopus sp.

Cloned(Commentary)

Cloned (Comment) Organism
expression in Escherichia coli Homo sapiens

Inhibitors

Inhibitors Comment Organism Structure
CH3COOK inhibits in presence of spermidine Bos taurus
CH3COOK
-
 Homo sapiens
CH3COOK inhibits in presence of spermidine Xenopus sp.
K3PO4 inhibits in presence of spermidine Bos taurus
K3PO4
-
 Homo sapiens
K3PO4 inhibits in presence of spermidine Xenopus sp.
poly(A)-binding protein PAB 1 inhibits; phased poly(A) shortening Homo sapiens

Localization

Localization Comment Organism GeneOntology No. Textmining
cytoplasm
-
 Homo sapiens 5737
-
nucleus
-
 Bos taurus 5634
-
nucleus
-
 Homo sapiens 5634
-

Metals/Ions

Metals/Ions Comment Organism Structure
K3PO4 absolute required in absence of spermidine Bos taurus
K3PO4 absolute required in absence of spermidine Xenopus sp.

Molecular Weight [Da]

Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
62000 74000
-
 Xenopus sp.
73500
-
 amino acid analysis Homo sapiens

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
poly(A) RNA + H2O Bos taurus
-
 5'-AMP + ?
-
 ?
poly(A) RNA + H2O Xenopus sp.
-
 5'-AMP + ?
-
 ?
poly(A) RNA + H2O Homo sapiens
-
 5'-AMP + ?
-
 ?

Organism

Organism UniProt Comment Textmining
Bos taurus
-
-
-
Homo sapiens O95453
-
-
Xenopus sp.
-
-
-

Purification (Commentary)

Purification (Comment) Organism
-
 Xenopus sp.
of the recombinant protein Homo sapiens

Source Tissue

Source Tissue Comment Organism Textmining
oocyte
-
 Homo sapiens
-
pancreas
-
 Bos taurus
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
poly(A) RNA + H2O
-
 Bos taurus 5'-AMP + ?
-
 ?
poly(A) RNA + H2O
-
 Xenopus sp. 5'-AMP + ?
-
 ?
poly(A) RNA + H2O
-
 Homo sapiens 5'-AMP + ?
-
 ?
poly(A)-mRNA + H2O
-
 Bos taurus 5'-AMP
-
 ?
poly(A)-mRNA + H2O DAN involved in oocyte maturation Xenopus sp. 5'-AMP
-
 ?
poly(A)-mRNA + H2O DAN involved in oocyte maturation Homo sapiens 5'-AMP
-
 ?

Synonyms

Synonyms Comment Organism
More
-
 Bos taurus
More similar enzyme: DAN: deanylating nuclease Homo sapiens