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Literature summary for 3.1.13.4 extracted from

  • Boeck, R.; Tarun, S., Jr.; Rieger, M.; Deardorff, J.A.; Muller-Auer, S.; Sachs, A.B.
    The yeast Pan2 protein is required for poly(A)-binding protein-stimulated poly(A)-nuclease activity (1996), J. Biol. Chem., 271, 432-438.
    View publication on PubMed

Activating Compound

Activating Compound Comment Organism Structure
Pan2 protein required for poly(A)-binding in poly(A) cleavage Saccharomyces cerevisiae

Molecular Weight [Da]

Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
161000
-
135000 polypeptide is not required for poly(A)-ribonuclease activity Saccharomyces cerevisiae

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
poly(A) RNA + H2O Saccharomyces cerevisiae
-
5'-AMP + ?
-
?

Organism

Organism UniProt Comment Textmining
Saccharomyces cerevisiae
-
several mutants
-

Purification (Commentary)

Purification (Comment) Organism
to homogeneity Saccharomyces cerevisiae

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
poly(A) RNA + H2O
-
Saccharomyces cerevisiae 5'-AMP + ?
-
?
poly(A)-mRNA + H2O PAN mutants have only mild effects on deadenylation Saccharomyces cerevisiae 5'-AMP
-
?

Synonyms

Synonyms Comment Organism
More similar enzyme: PAN: PAB-dependent poly(A) ribonuclease Saccharomyces cerevisiae