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Literature summary for 3.1.13.4 extracted from

  • Sachs, A.B.; Deardorff, J.A.
    Translation initiation requires the PAB-dependent poly(A) ribonuclease in yeast (1992), Cell, 70, 961-973.
    View publication on PubMed
Search for more literature for 3.1.13.4

Activating Compound

Activating Compound Comment Organism Structure
poly(A)-binding protein PAB 1 PAB 1 required Saccharomyces cerevisiae

Cloned(Commentary)

Cloned (Comment) Organism
expression in yeast Saccharomyces cerevisiae
mutagenized plasmids Saccharomyces cerevisiae

Molecular Weight [Da]

Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
161000
-
 amino acid analysis Saccharomyces cerevisiae
161000
-
 76000 and 135000, SDS-PAGE Saccharomyces cerevisiae

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
poly(A) RNA + H2O Saccharomyces cerevisiae
-
 5'-AMP + ?
-
 ?

Organism

Organism UniProt Comment Textmining
Saccharomyces cerevisiae
-
 several mutants
-

Purification (Commentary)

Purification (Comment) Organism
to homogeneity Saccharomyces cerevisiae

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
poly(A) RNA + H2O
-
 Saccharomyces cerevisiae 5'-AMP + ?
-
 ?
poly(A)-mRNA + H2O absolute requirement for a ribonucleoprotein Saccharomyces cerevisiae 5'-AMP
-
 ?

Synonyms

Synonyms Comment Organism
More similar enzyme: PAN: PAB-dependent poly(A) ribonuclease Saccharomyces cerevisiae