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Literature summary for 3.1.13.2 extracted from

  • Schultz, S.J.; Zhang, M.; Champoux, J.J.
    Recognition of internal cleavage sites by retroviral RNases H (2004), J. Mol. Biol., 344, 635-652.
    View publication on PubMed

Metals/Ions

Metals/Ions Comment Organism Structure
Mg2+
-
Moloney murine leukemia virus
Mg2+
-
Human immunodeficiency virus 1

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
additional information Moloney murine leukemia virus the enzyme is essential to complete retroviral replication ?
-
?
additional information Human immunodeficiency virus 1 the enzyme is essential to complete retroviral replication ?
-
?

Organism

Organism UniProt Comment Textmining
Human immunodeficiency virus 1
-
i.e. HIV-1
-
Moloney murine leukemia virus
-
i.e. M-MuLV
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
DNA-RNA hybrid + H2O in vitro synthesis of substrates, overview Moloney murine leukemia virus ?
-
?
DNA-RNA hybrid + H2O in vitro synthesis of substrates, overview Human immunodeficiency virus 1 ?
-
?
additional information the enzyme is essential to complete retroviral replication Moloney murine leukemia virus ?
-
?
additional information the enzyme is essential to complete retroviral replication Human immunodeficiency virus 1 ?
-
?
additional information the enzyme recognizes 3' ends of DNA and 5' ends of RNA for cleavage, the enzyme cleaves downstream of a nick, recognition of internal cleavage sites, influence of 5' end position of upstream RNA on cleavage of downstream RNA, overview Moloney murine leukemia virus ?
-
?
additional information the enzyme recognizes 3' ends of DNA and 5' ends of RNA for cleavage, the enzyme cleaves downstream of a nick, recognition of internal cleavage sites, influence of 5' end position of upstream RNA on cleavage of downstream RNA, overview Human immunodeficiency virus 1 ?
-
?

Synonyms

Synonyms Comment Organism
retroviral RNase H
-
Moloney murine leukemia virus
retroviral RNase H
-
Human immunodeficiency virus 1

Temperature Optimum [°C]

Temperature Optimum [°C] Temperature Optimum Maximum [°C] Comment Organism
37
-
assay at Moloney murine leukemia virus
37
-
assay at Human immunodeficiency virus 1

pH Optimum

pH Optimum Minimum pH Optimum Maximum Comment Organism
8
-
assay at Moloney murine leukemia virus
8
-
assay at Human immunodeficiency virus 1