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Literature summary for 3.1.13.2 extracted from

  • Keller, W.; Crouch, R.
    Degradation of DNA RNA hybrids by ribonuclease H and DNA polymerases of cellular and viral origin (1972), Proc. Natl. Acad. Sci. USA, 69, 3360-3364.
    View publication on PubMedView publication on EuropePMC
Search for more literature for 3.1.13.2

Inhibitors

Inhibitors Comment Organism Structure
KCl at concentrations above 0.05 M Avian myeloblastosis virus
KCl at concentrations above 0.05 M Rous-associated virus

Metals/Ions

Metals/Ions Comment Organism Structure
Mg2+ requires Mg2+ Avian myeloblastosis virus
Mg2+ requires Mg2+ Rous-associated virus

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
DNA-RNA hybrid duplex + H2O Avian myeloblastosis virus
-
 oligonucleotides terminated with 5'-phosphate and 3'-hydroxyl moiety
-
 ?
DNA-RNA hybrid duplex + H2O Rous-associated virus
-
 oligonucleotides terminated with 5'-phosphate and 3'-hydroxyl moiety
-
 ?

Organism

Organism UniProt Comment Textmining
Avian myeloblastosis virus
-
-
-
More
-
 retrovirus: RNaseH and transcriptase are present in a single polypeptide
-
Rous-associated virus
-
 RAV-1
-

Purification (Commentary)

Purification (Comment) Organism
-
 Avian myeloblastosis virus
-
 Rous-associated virus

Specific Activity [micromol/min/mg]

Specific Activity Minimum [µmol/min/mg] Specific Activity Maximum [µmol/min/mg] Comment Organism
0.1
-
-
 Avian myeloblastosis virus
0.1
-
-
 Rous-associated virus

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
DNA-RNA hybrid duplex + H2O
-
 Avian myeloblastosis virus oligonucleotides terminated with 5'-phosphate and 3'-hydroxyl moiety
-
 ?
DNA-RNA hybrid duplex + H2O
-
 Rous-associated virus oligonucleotides terminated with 5'-phosphate and 3'-hydroxyl moiety
-
 ?