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Literature summary for 3.1.13.2 extracted from
- Reverse transcriptase-associated ribonuclease H does not require zinc for catalysis (1979), J. Biol. Chem., 254, 4756-4759.
Inhibitors
| Inhibitors | Comment | Organism | Structure |
|---|---|---|---|
| additional information | not: o-phenanthroline | Avian myeloblastosis virus | |
| additional information | not: o-phenanthroline | Mason-Pfizer monkey virus | |
| additional information | not: o-phenanthroline | mouse mammary tumor virus | |
| additional information | not: o-phenanthroline | Rauscher leukemia virus | |
| additional information | not: o-phenanthroline | Woolly monkey sarcoma virus |
Metals/Ions
| Metals/Ions | Comment | Organism | Structure |
|---|---|---|---|
| additional information | - |
Mason-Pfizer monkey virus | |
| additional information | - |
Rauscher leukemia virus | |
| additional information | - |
mouse mammary tumor virus | |
| additional information | - |
Woolly monkey sarcoma virus | |
| additional information | zinc is not involved in catalysis | Avian myeloblastosis virus |
Natural Substrates/ Products (Substrates)
| Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| DNA-RNA hybrid duplex + H2O | Avian myeloblastosis virus | - |
oligonucleotides terminated with 5'-phosphate and 3'-hydroxyl moiety | - |
? |  |
| DNA-RNA hybrid duplex + H2O | Mason-Pfizer monkey virus | - |
oligonucleotides terminated with 5'-phosphate and 3'-hydroxyl moiety | - |
? | |
| DNA-RNA hybrid duplex + H2O | Rauscher leukemia virus | - |
oligonucleotides terminated with 5'-phosphate and 3'-hydroxyl moiety | - |
? | |
| DNA-RNA hybrid duplex + H2O | mouse mammary tumor virus | - |
oligonucleotides terminated with 5'-phosphate and 3'-hydroxyl moiety | - |
? | |
| DNA-RNA hybrid duplex + H2O | Woolly monkey sarcoma virus | - |
oligonucleotides terminated with 5'-phosphate and 3'-hydroxyl moiety | - |
? | |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Avian myeloblastosis virus | - |
- |
- |
| Mason-Pfizer monkey virus | - |
- |
- |
| More | - |
retrovirus: RNaseH and transcriptase are present in a single polypeptide | - |
| mouse mammary tumor virus | - |
- |
- |
| Rauscher leukemia virus | - |
RLV | - |
| Woolly monkey sarcoma virus | - |
- |
- |
Purification (Commentary)
| Purification (Comment) | Organism |
|---|---|
- |
Avian myeloblastosis virus |
- |
Mason-Pfizer monkey virus |
- |
Rauscher leukemia virus |
- |
mouse mammary tumor virus |
- |
Woolly monkey sarcoma virus |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| DNA-RNA hybrid duplex + H2O | - |
Avian myeloblastosis virus | oligonucleotides terminated with 5'-phosphate and 3'-hydroxyl moiety | - |
? | |
| DNA-RNA hybrid duplex + H2O | - |
Mason-Pfizer monkey virus | oligonucleotides terminated with 5'-phosphate and 3'-hydroxyl moiety | - |
? | |
| DNA-RNA hybrid duplex + H2O | - |
Rauscher leukemia virus | oligonucleotides terminated with 5'-phosphate and 3'-hydroxyl moiety | - |
? | |
| DNA-RNA hybrid duplex + H2O | - |
mouse mammary tumor virus | oligonucleotides terminated with 5'-phosphate and 3'-hydroxyl moiety | - |
? | |
| DNA-RNA hybrid duplex + H2O | - |
Woolly monkey sarcoma virus | oligonucleotides terminated with 5'-phosphate and 3'-hydroxyl moiety | - |
? | |
| additional information | not: ds DNA | Avian myeloblastosis virus | ? | - |
? | |
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