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Literature summary for 3.1.13.2 extracted from
- Mechanism of action of ribonuclease H isolated from avian myeloblastosis virus and Escherichia coli (1973), Proc. Natl. Acad. Sci. USA, 70, 466-470.
Activating Compound
| Activating Compound | Comment | Organism | Structure |
|---|---|---|---|
| Stimulatory protein | - |
Avian myeloblastosis virus |
Natural Substrates/ Products (Substrates)
| Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| DNA-RNA hybrid duplex + H2O | Avian myeloblastosis virus | - |
oligonucleotides terminated with 5'-phosphate and 3'-hydroxyl moiety | - |
? |  |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Avian myeloblastosis virus | - |
- |
- |
| More | - |
retrovirus: RNaseH and transcriptase are present in a single polypeptide | - |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| DNA-RNA hybrid duplex + H2O | - |
Avian myeloblastosis virus | oligonucleotides terminated with 5'-phosphate and 3'-hydroxyl moiety | - |
? | |
| DNA-RNA hybrid duplex + H2O | limited hydrolysis of ribopolymers when complementary DNA strand is missing or in presence of a complementary RNA strand | Avian myeloblastosis virus | oligonucleotides terminated with 5'-phosphate and 3'-hydroxyl moiety | - |
? | |
| additional information | not: poly(rU)-poly(dA), DNA-RNA hybrids without a free RNA-end | Avian myeloblastosis virus | ? | - |
? | |
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