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Literature summary for 3.1.11.5 extracted from

  • Vlahovic, K.; Petranovic, M.; Zahradka, D.; Petranovic, D.
    Progressive loss of lambda prophage recombinogenicity in UV-irradiated Escherichia coli: the role of RecBCD enzyme (2000), Res. Microbiol., 151, 727-738.
    View publication on PubMed

Protein Variants

Protein Variants Comment Organism
additional information in mutants carrying either recB2109 or recD1903, which do not exhibit significant nuclease activities, the prophage progressively loses its capacity for both site-specific and general recombination Escherichia coli

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
additional information Escherichia coli The enzyme is involved in the radiation-induced process know as prophage inactivation. The helicase activity of enzyme is responsible for the progressive loss of prophage recombinogenicity. This loss is most probably a consequence of the unsuccessful enzyme-dependent recombinational repair of double-stranded breaks in the cell chromosome, during which some structures unsuitable for further recombination reactions may be produced. ?
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Organism

Organism UniProt Comment Textmining
Escherichia coli
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Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
additional information The enzyme is involved in the radiation-induced process know as prophage inactivation. The helicase activity of enzyme is responsible for the progressive loss of prophage recombinogenicity. This loss is most probably a consequence of the unsuccessful enzyme-dependent recombinational repair of double-stranded breaks in the cell chromosome, during which some structures unsuitable for further recombination reactions may be produced. Escherichia coli ?
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