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Literature summary for 3.1.11.4 extracted from
- Methods for limiting the action of SP3 DNAase and for the determination of the direction of hydrolysis of processive exonucleases (1979), Biochim. Biophys. Acta, 563, 393-399.
Application
| Application | Comment | Organism |
|---|---|---|
| analysis | determination of the direction of hydrolysis of processive exonucleases | Enterobacteria phage SP |
Inhibitors
| Inhibitors | Comment | Organism | Structure |
|---|---|---|---|
| N-cyclohexyl-N'-beta-(4-methylmorpholinium)-ethylcarbodiimide-derivatized DNA | blocks enzyme activity absolutely, inhibition independent of nucleotide sequences | Enterobacteria phage SP |
Natural Substrates/ Products (Substrates)
| Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| single-stranded DNA + H2O | Enterobacteria phage SP | - |
? | - |
? |  |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Enterobacteria phage SP | - |
- |
- |
Source Tissue
| Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|
| infected cell | infected Bacillus subtilis | Enterobacteria phage SP | - |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| oligo- and polydeoxyribonucleotides + H2O | hydrolysis on polynucleotides from the 5-termini of single-stranded DNA | Enterobacteria phage SP | dinucleotide + oligonucleotide | - |
? | |
| single-stranded DNA + H2O | - |
Enterobacteria phage SP | ? | - |
? | |
| sorbitol-derivatized octanucleotides + H2O | - |
Enterobacteria phage SP | dinucleotide + oligonucleotide | - |
? | |
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