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Literature summary for 3.1.11.1 extracted from

  • Yao, Y.; Wang, Q.; Hao, Y.; Tan, Z.
    An exonuclease I hydrolysis assay for evaluating G-quadruplex stabilization by small molecules (2007), Nucleic Acids Res., 35, e68/1-e68/9.
    View publication on PubMedView publication on EuropePMC

Application

Application Comment Organism
analysis an exonuclease I hydrolysis assay for evaluating G-quadruplex stabilization by small molecules Escherichia coli

Organism

Organism UniProt Comment Textmining
Escherichia coli P04995
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-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
single-stranded oligodeoxyribonucleotide + H2O quadruplex-forming and a non-quadruplex-forming oligomer as substrates.The formation of quadruplex in the oligomer inhibits its hydrolysis and quadruplex stabilization enhances the inhibition Escherichia coli single-stranded oligodeoxyribonucleotide + nucleoside 5'-monophosphate
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Synonyms

Synonyms Comment Organism
exonuclease I
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Escherichia coli