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Literature summary for 3.1.11.1 extracted from

  • Schmutte, C.; Sadoff, M.M.; Shim, K.S.; Acharya, S.; Fishel, R.
    The interaction of DNA mismatch repair proteins with human exonuclease I (2001), J. Biol. Chem., 276, 33011-33018.
    View publication on PubMed

Organism

Organism UniProt Comment Textmining
Homo sapiens
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Reaction

Reaction Comment Organism Reaction ID
Exonucleolytic cleavage in the 3'- to 5'- direction to yield nucleoside 5'-phosphates study of interaction between enzyme and mismatch repair proteins MLH1, MLH2 and MLH3. The enzyme binds strongly to MLH1 and forms an immunoprecipitable complex with MLH1/MLH2 in vivo Homo sapiens