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Literature summary for 3.1.1.8 extracted from

  • Anglister, L.; Etlin, A.; Finkel, E.; Durrant, A.R.; Lev-Tov, A.
    Cholinesterases in development and disease (2008), Chem. Biol. Interact., 175, 92-100.
    View publication on PubMed
Search for more literature for 3.1.1.8

Inhibitors

Inhibitors Comment Organism Structure
iso-ompa specific for BuChE Mus musculus

Localization

Localization Comment Organism GeneOntology No. Textmining
extracellular serum Mus musculus
-
-

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
additional information Mus musculus butyrylcholinesterase to acetylcholinesterase ratio in mouse sera decreases from 6:1 in wild-type control to 3:1 in mdx-mice ?
-
 ?

Organism

Organism UniProt Comment Textmining
Mus musculus
-
 wild-type mice and mdx-mice with adult mdx-muscles malformed with distorted neuromuscular junctions and impaired regulation of acetylcholine receptors
-

Source Tissue

Source Tissue Comment Organism Textmining
additional information butyrylcholinesterase is abundant in the central and peripheral nervous system and also in other tissues Mus musculus
-
nervous system central and perpheral Mus musculus
-
serum BuChE activity is markedly lower in serum of mdx-mice than in wild-type mouse serum, overview Mus musculus
-
skeletal muscle
-
 Mus musculus
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
butyrylthiocholine + H2O detection using 5,5'-dithiobis(2-nitrobenzoic acid) Mus musculus butyrate + thiocholine
-
 ?
additional information butyrylcholinesterase to acetylcholinesterase ratio in mouse sera decreases from 6:1 in wild-type control to 3:1 in mdx-mice Mus musculus ?
-
 ?

Synonyms

Synonyms Comment Organism
BuChE
-
 Mus musculus
butyrylcholinesterase
-
 Mus musculus