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Literature summary for 3.1.1.8 extracted from
- Human serum cholinesterase from liver pathological samples exhibit highly elevated aryl acylamidase activity (2007), Clin. Chim. Acta, 380, 151-156.
Inhibitors
| Inhibitors | Comment | Organism | Structure |
|---|---|---|---|
| BW284c51 | i.e. bis(4-allyl dimethyl ammoniumphenyl) pentane-3-one dibromide | Homo sapiens |  |
| iso-ompa | i.e. tetaisopropyl diphosphoramide | Homo sapiens | |
Localization
| Localization | Comment | Organism | GeneOntology No. | Textmining |
|---|---|---|---|---|
| extracellular | - |
Homo sapiens | - |
- |
Natural Substrates/ Products (Substrates)
| Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| butyrylthiocholine + H2O | Homo sapiens | - |
thiocholine + butyrate | - |
? | |
| additional information | Homo sapiens | the enzyme is assessed as a marker for liver pathologies, patients with diminished BChE activity do not have increased BChE aryl acylamidase activity, but the overall aryl acylamidase activity is increased, overview | ? | - |
? | |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Homo sapiens | - |
- |
- |
Source Tissue
| Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|
| additional information | ubiquitous enzyme | Homo sapiens | - |
| serum | - |
Homo sapiens | - |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| butyrylthiocholine + H2O | - |
Homo sapiens | thiocholine + butyrate | - |
? | |
| additional information | the enzyme is assessed as a marker for liver pathologies, patients with diminished BChE activity do not have increased BChE aryl acylamidase activity, but the overall aryl acylamidase activity is increased, overview | Homo sapiens | ? | - |
? | |
Synonyms
| Synonyms | Comment | Organism |
|---|---|---|
| BChE | - |
Homo sapiens |
| butyrylcholinesterase | - |
Homo sapiens |
| non-specific cholinesterase | - |
Homo sapiens |
| pseudo choline esterase | - |
Homo sapiens |
| serum cholinesterase | - |
Homo sapiens |
Temperature Optimum [°C]
| Temperature Optimum [°C] | Temperature Optimum Maximum [°C] | Comment | Organism |
|---|---|---|---|
| 37 | - |
assay at | Homo sapiens |
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Release 2023.1 (January 2023)
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