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Literature summary for 3.1.1.7 extracted from

  • Lv, W.; Xue, Y.
    Prediction of acetylcholinesterase inhibitors and characterization of correlative molecular descriptors by machine learning methods (2010), Eur. J. Med. Chem., 45, 1167-1172.
    View publication on PubMed

Application

Application Comment Organism
drug development AChE is an important drug target and its inhibitors prove useful in the symptomatic treatment of Alzheimer's disease Electrophorus electricus

Inhibitors

Inhibitors Comment Organism Structure
additional information inhibitor design and evaluation using cardanol derivatives and the B3LYP method, structures with substitution by N,N-dimethycarbamoyl, N,N-dimethylamine, and pyrrolidine groups are better correlated to rivastigmine, and represent possible AChE inhibitors against Alzheimer's disease, overview. Cardanol is a non-isoprenoid phenolic lipid of cashew Anacardium occidentale nut-shell liquid Electrophorus electricus

Organism

Organism UniProt Comment Textmining
Electrophorus electricus
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-
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Synonyms

Synonyms Comment Organism
AChE
-
Electrophorus electricus