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Literature summary for 3.1.1.7 extracted from

  • Gao, J.R.; Zhu, K.Y.
    An acetylcholinesterase purified from the greenbug (Schizaphis graminum) with some unique enzymological and pharmacological characteristics (2001), Insect Biochem. Mol. Biol., 31, 1095-1104.
    View publication on PubMed
Search for more literature for 3.1.1.7

Inhibitors

Inhibitors Comment Organism Structure
1,5-bis(4-allyldimethylammoniumphenyl)-pentan-3-one dibromide i.e. BW284c51, 98% inhibition at 0.01 mM Schizaphis graminum
eserine 98% inhibition at 0.01 mM Schizaphis graminum
ethopropazine 7% inhibition at 0.01 mM Schizaphis graminum

KM Value [mM]

KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
0.031
-
 propionylthiocholine
-
 Schizaphis graminum
0.0334
-
 S-butyrylthiocholine
-
 Schizaphis graminum
0.0576
-
 acetylthiocholine
-
 Schizaphis graminum
0.061
-
 acetyl-(beta-methyl)thiocholine
-
 Schizaphis graminum

Molecular Weight [Da]

Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
72000
-
 x * 72000, SDS-PAGE Schizaphis graminum
129000
-
 gel filtration Schizaphis graminum

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
acetylcholine + H2O Schizaphis graminum
-
 choline + acetate
-
 ?

Organism

Organism UniProt Comment Textmining
Schizaphis graminum
-
 greenbug
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
acetyl-(beta-methyl)thiocholine + H2O
-
 Schizaphis graminum (beta-methyl)thiocholine + acetate
-
 ?
acetylcholine + H2O
-
 Schizaphis graminum choline + acetate
-
 ?
acetylthiocholine + H2O
-
 Schizaphis graminum thiocholine + acetate
-
 ?
propionylthiocholine + H2O
-
 Schizaphis graminum thiocholine + propionate
-
 ?
S-butyrylthiocholine + H2O
-
 Schizaphis graminum thiocholine + butyrate
-
 ?

Subunits

Subunits Comment Organism
? x * 72000, SDS-PAGE Schizaphis graminum

pI Value

Organism Comment pI Value Maximum pI Value
Schizaphis graminum three isoforms: 1 major form with pI 7.3 and 2 minor forms with pI 6.3 and pI 7.1, isoelectric focusing 6.8 6.3
Schizaphis graminum three isoforms: 1 major form with pI 7.3 and 2 minor forms with pI 6.3 and pI 7.1, isoelectric focusing
-
 7.1
Schizaphis graminum three isoforms: 1 major form with pI 7.3 and 2 minor forms with pI 6.3 and pI 7.1, isoelectric focusing 7.4 7.3