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Literature summary for 3.1.1.5 extracted from
- Purification and characterization of lysophospholipase-transacylase (h-LPTA) from a highly virulant strain of Candida albicans (1995), Biochim. Biophys. Acta, 1257, 181-188.
Activating Compound
| Activating Compound | Comment | Organism | Structure |
|---|---|---|---|
| palmitoylcarnitine | stimulates hydrolase activity | Candida albicans |  |
Inhibitors
| Inhibitors | Comment | Organism | Structure |
|---|---|---|---|
| 1-stearoyl-2-arachidonoyl-sn-glycero-3-phosphate | - |
Candida albicans | |
| albumin | - |
Candida albicans | |
| NEM | transacylase activity | Candida albicans | |
| palmitoylcarnitine | transacylase activity | Candida albicans | |
KM Value [mM]
| KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
|---|---|---|---|---|---|
| 0.0606 | - |
1-palmitoyl-sn-glycero-3-phosphocholine | - |
Candida albicans | |
Molecular Weight [Da]
| Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
|---|---|---|---|
| 84000 | - |
x * 84000, SDS-PAGE | Candida albicans |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Candida albicans | - |
- |
- |
Posttranslational Modification
| Posttranslational Modification | Comment | Organism |
|---|---|---|
| side-chain modification | glycoprotein | Candida albicans |
Purification (Commentary)
| Purification (Comment) | Organism |
|---|---|
- |
Candida albicans |
Specific Activity [micromol/min/mg]
| Specific Activity Minimum [µmol/min/mg] | Specific Activity Maximum [µmol/min/mg] | Comment | Organism |
|---|---|---|---|
| 117 | - |
fatty acid release | Candida albicans |
| 459 | - |
phosphatidylcholine formation | Candida albicans |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| 1-palmitoyl-sn-glycero-3-phosphocholine + H2O | - |
Candida albicans | palmitic acid + glycero-3-phosphocholine | - |
? | |
| lysophosphatidylcholine + H2O | - |
Candida albicans | glycerophosphorylcholine + unesterified fatty acid | - |
? | |
| lysophosphatidylcholine + lysophosphatidylcholine | - |
Candida albicans | glycerophosphocholine + phosphatidylcholine | - |
? | |
Subunits
| Subunits | Comment | Organism |
|---|---|---|
| ? | x * 84000, SDS-PAGE | Candida albicans |
Synonyms
| Synonyms | Comment | Organism |
|---|---|---|
| h-LPTA | - |
Candida albicans |
| lysophospholipase-transacylase | - |
Candida albicans |
pH Optimum
| pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
|---|---|---|---|
| 6 | - |
- |
Candida albicans |
pH Range
| pH Minimum | pH Maximum | Comment | Organism |
|---|---|---|---|
| 4 | 8 | pH 4.0: about 65% of maximal activity, pH 8.0: about 40% of maximal activity, production of phosphatidylcholine | Candida albicans |
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