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Literature summary for 3.1.1.5 extracted from

  • Sugatani, J.; Okumura, T.; Saito, K.
    Studies of a phospholipase B from Penicillium notatum. Substrate specificity and properties of active site (1980), Biochim. Biophys. Acta, 620, 372-386.
    View publication on PubMed
Search for more literature for 3.1.1.5

Activating Compound

Activating Compound Comment Organism Structure
chloramphenicol stimulates phospholipase B activity Penicillium chrysogenum
Triton X-100 stimulates phospholipase B activity Penicillium chrysogenum

Inhibitors

Inhibitors Comment Organism Structure
2-Hydroxy-5-nitrobenzyl bromide
-
 Penicillium chrysogenum
chlorpromazine at low concentrations significantly stimulates phospholipase B activity of native enzyme, strong stimulation at high concentrations Penicillium chrysogenum
N-bromosuccinimide
-
 Penicillium chrysogenum
Phenylglyoxal
-
 Penicillium chrysogenum

KM Value [mM]

KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
0.82
-
 1,2-dipalmitoyl-sn-glycero-3-phosphocholine
-
 Penicillium chrysogenum
1
-
 1,2-didecanoyl-sn-glycero-3-phosphocholine
-
 Penicillium chrysogenum
2.9
-
 1,2-dioctanoyl-sn-glycero-3-phosphocholine
-
 Penicillium chrysogenum

Organism

Organism UniProt Comment Textmining
Penicillium chrysogenum
-
-
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
1,2-didecanoyl-sn-glycero-3-phosphocholine + H2O
-
 Penicillium chrysogenum ?
-
 ?
1,2-dioctanoyl-sn-glycero-3-phosphocholine + H2O
-
 Penicillium chrysogenum ?
-
 ?
1,2-dipalmitoyl-sn-glycero-3-phosphocholine + H2O
-
 Penicillium chrysogenum ?
-
 ?
1-palmitoyl-sn-glycero-3-phosphocholine + H2O
-
 Penicillium chrysogenum palmitic acid + glycero-3-phosphocholine
-
 ?
2,3-dipalmitoyl-sn-glycero-1-phosphocholine + H2O
-
 Penicillium chrysogenum monopalmitoyl-sn-glycero-1-phosphocholine + palmitic acid
-
 ?
2-palmitoyl-sn-glycero-3-phosphocholine + H2O
-
 Penicillium chrysogenum palmitic acid + glycero-3-phosphocholine
-
 ?
lysophosphatidylcholine + H2O
-
 Penicillium chrysogenum glycerophosphorylcholine + unesterified fatty acid
-
 ?
monooleoylglycerol + H2O
-
 Penicillium chrysogenum oleic acid + glycerol
-
 ?
monopalmitoylglycerol + H2O
-
 Penicillium chrysogenum palmitic acid + glycerol
-
 ?
phosphatidylcholine + H2O hydrolysis of the 1-acly ester bond and the 2-acyl ester bond, phospholipase B activity Penicillium chrysogenum lysophosphatidylcholine + glycerophosphorylcholine + a carboxylate
-
 ?

pH Optimum

pH Optimum Minimum pH Optimum Maximum Comment Organism
4
-
 monoacylglycerols Penicillium chrysogenum