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Literature summary for 3.1.1.47 extracted from

  • Karasawa, K.; Yato, M.; Setaka, M.; Nojima, S.
    Purification and characterization of platelet-activating factor acetylhydrolase from peritoneal fluid obtained from guinea pigs after endotoxin shock (1994), J. Biochem., 116, 374-379.
    View publication on PubMed
Search for more literature for 3.1.1.47

Inhibitors

Inhibitors Comment Organism Structure
diisopropylfluorophosphate
-
 Cavia porcellus
p-bromophenacyl bromide
-
 Cavia porcellus
phenylmethylsulfonyl fluoride
-
 Cavia porcellus

Molecular Weight [Da]

Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
63000
-
 gel filtration Cavia porcellus

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
1-O-alkyl-2-acetyl-sn-glycero-3-phosphocholine + H2O Cavia porcellus inactivation of the substrate which represents a wide variety of bioactivities, including hypotension, platelat activation, bronchoconstriction ?
-
 ?

Organism

Organism UniProt Comment Textmining
Cavia porcellus
-
-
-

Purification (Commentary)

Purification (Comment) Organism
-
 Cavia porcellus

Source Tissue

Source Tissue Comment Organism Textmining
ascites
-
 Cavia porcellus
-

Specific Activity [micromol/min/mg]

Specific Activity Minimum [µmol/min/mg] Specific Activity Maximum [µmol/min/mg] Comment Organism
20.3
-
-
 Cavia porcellus

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
1-hexadecyl-2-acetyl-sn-glycerol-3-phosphocholine + H2O i.e. PAF Cavia porcellus 1-hexadecyl-sn-glycerol-3-phosphocholine + acetate
-
 ?
1-hexadecyl-2-glutaryl-sn-glycero-3-phosphocholine + H2O
-
 Cavia porcellus 1-hexadecyl-glycero-3-phosphocholine + glutarate
-
 ?
1-hexadecyl-2-succinyl-sn-glycero-3-phosphocholine + H2O
-
 Cavia porcellus 1-hexadecyl-glycero-3-phosphocholine + succinate
-
 ?
1-O-alkyl-2-acetyl-sn-glycero-3-phosphocholine + H2O inactivation of the substrate which represents a wide variety of bioactivities, including hypotension, platelat activation, bronchoconstriction Cavia porcellus ?
-
 ?

Subunits

Subunits Comment Organism
monomer 1 * 63000, SDS-PAGE Cavia porcellus