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Literature summary for 3.1.1.47 extracted from

  • Rizos, E.; Tambaki, A.P.; Gazi, I.; Tselepis, A.D.; Elisaf, M.
    Lipoprotein-associated PAF-acetylhydrolase activity in subjects with the metabolic syndrome (2005), Prostaglandins Leukot. Essent. Fatty Acids, 72, 203-209.
    View publication on PubMed

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
1-O-alkyl-2-acetyl-sn-glycero-3-phosphocholine + H2O Homo sapiens regulation of platelet-activating factor, important role in inflammation and in atherosclerotic processes related to the metabolic syndrome 1-O-alkyl-sn-glycero-3-phosphocholine + acetate
-
?
additional information Homo sapiens enzyme activity is suggested to be an important marker for atherogenicity ?
-
?
oxidized phospholipids + H2O Homo sapiens degradation of oxidized phospholipids formed during the oxidative modification of low-density lipoprotein ?
-
?

Organism

Organism UniProt Comment Textmining
Homo sapiens
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patients suffering from metabolic syndrome and control subjects, higher enzyme activity in the metabolic syndrome patients group compared with the control group
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Source Tissue

Source Tissue Comment Organism Textmining
blood plasma main part of enzyme associated with low-density lipoprotein, small portion of enzyme associated with high-density lipoprotein Homo sapiens
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
1-O-alkyl-2-acetyl-sn-glycero-3-phosphocholine + H2O regulation of platelet-activating factor, important role in inflammation and in atherosclerotic processes related to the metabolic syndrome Homo sapiens 1-O-alkyl-sn-glycero-3-phosphocholine + acetate
-
?
1-O-hexadecyl-2-acetyl-sn-glycero-3-phosphocholine + H2O
-
Homo sapiens 1-O-hexadecyl-sn-glycerol-3-phosphocholine + acetate
-
?
additional information enzyme activity is suggested to be an important marker for atherogenicity Homo sapiens ?
-
?
oxidized phospholipids + H2O degradation of oxidized phospholipids formed during the oxidative modification of low-density lipoprotein Homo sapiens ?
-
?