Localization | Comment | Organism | GeneOntology No. | Textmining |
---|---|---|---|---|
soluble | - |
Sus scrofa | - |
- |
Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
---|---|---|---|
26000 | - |
1 * 26000 + 1 * 28000, dimer consisting of alpha1 and alpha2 subunit, SDS-PAGE, native mass by gel filtration | Sus scrofa |
28000 | - |
1 * 26000 + 1 * 28000, dimer consisting of alpha1 and alpha2 subunit, SDS-PAGE, native mass by gel filtration | Sus scrofa |
28000 | - |
2 * 28000, dimer consisting of two alpha2 subunits, SDS-PAGE, native mass by gel filtration | Sus scrofa |
60000 | - |
gel filtration | Sus scrofa |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
1-O-alkyl-2-acetyl-sn-glycero-3-phosphocholine + H2O | Sus scrofa | enzyme from red blood cells is not involved in the degradation of platelet-activating factor accumulated in blood | 1-O-alkyl-sn-glycero-3-phosphocholine + acetate | - |
? | |
phospholipid + H2O | Sus scrofa | degradation of phospholipids produced by oxidative stress | ? | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Sus scrofa | - |
- |
- |
Purification (Comment) | Organism |
---|---|
- |
Sus scrofa |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
blood | red blood cells | Sus scrofa | - |
Specific Activity Minimum [µmol/min/mg] | Specific Activity Maximum [µmol/min/mg] | Comment | Organism |
---|---|---|---|
0.176 | - |
purified enzyme, 37°C, pH 7.0 | Sus scrofa |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
1-O-alkyl-2-acetyl-sn-glycero-3-phosphocholine + H2O | enzyme from red blood cells is not involved in the degradation of platelet-activating factor accumulated in blood | Sus scrofa | 1-O-alkyl-sn-glycero-3-phosphocholine + acetate | - |
? | |
1-O-hexadecyl-2-acetyl-sn-glycero-3-phosphocholine + H2O | - |
Sus scrofa | 1-O-hexadecyl-sn-glycerol-3-phosphocholine + acetate | - |
? | |
phospholipid + H2O | degradation of phospholipids produced by oxidative stress | Sus scrofa | ? | - |
? |
Subunits | Comment | Organism |
---|---|---|
dimer | 1 * 26000 + 1 * 28000, dimer consisting of alpha1 and alpha2 subunit, SDS-PAGE, native mass by gel filtration | Sus scrofa |
dimer | 2 * 28000, dimer consisting of two alpha2 subunits, SDS-PAGE, native mass by gel filtration | Sus scrofa |
Synonyms | Comment | Organism |
---|---|---|
PAF-AH | - |
Sus scrofa |
platelet-activating factor-acetylhydrolase | - |
Sus scrofa |