Any feedback?
Please rate this page
(literature.php)
(0/150)

BRENDA support

Literature summary for 3.1.1.47 extracted from

  • Min, J.H.; Wilder, C.; Aoki, J.; Arai, H.; Inoue, K.; Paul, L.; Gelb, M.H.
    Platelet-activating factor acetylhydrolases: broad substrate specificity and lipoprotein binding does not modulate the catalytic properties of the plasma enzyme (2001), Biochemistry, 40, 4539-4549.
    View publication on PubMed
Search for more literature for 3.1.1.47

KM Value [mM]

KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
0.005
-
 2-acetyl-1-hexadecyl-sn-glycero-3-phosphocholine below, plasma isozyme, pH 7.5, 22°C Homo sapiens
0.005
-
 1,2-dioctanoyl-sn-glycerol below, plasma isozyme, pH 7.5, 22°C Homo sapiens
0.005
-
 2-acetyl-1-octadecyl-sn-glycero-3-phosphocholine below, plasma isozyme, pH 7.5, 22°C Homo sapiens
0.005
-
 1-acetyl-2-hexadecyl-sn-glycero-3-phosphocholine below, plasma isozyme, pH 7.5, 22°C Homo sapiens
0.005
-
 didecanoyl-phosphocholine below, plasma isozyme, pH 7.5, 22°C Homo sapiens
0.005
-
 1,2-dioctanoylethyleneglycol below, plasma isozyme, pH 7.5, 22°C Homo sapiens
0.006
-
 1-oleoyl-2-acetyl-sn-glycerol plasma isozyme, pH 7.5, 22°C Homo sapiens
0.011
-
 1,2-didecanoyl-sn-glycerol plasma isozyme, pH 7.5, 22°C Homo sapiens
0.047
-
 dioctanoyl-phosphocholine plasma isozyme, pH 7.5, 22°C Homo sapiens
0.055
-
 octyl acetate plasma isozyme, pH 7.5, 22°C Homo sapiens
0.086
-
 1-decanoyl-rac-glycerol plasma isozyme, pH 7.5, 22°C Homo sapiens
0.136
-
 tributyryl-glycerol plasma isozyme, pH 7.5, 22°C Homo sapiens
1.4
-
 1-octanoyl-rac-glycerol plasma isozyme, pH 7.5, 22°C Homo sapiens
4.7
-
 dibutanoyl-phosphocholine plasma isozyme, pH 7.5, 22°C Homo sapiens
63
-
 butyl acetate plasma isozyme, pH 7.5, 22°C Homo sapiens
131
-
 triacetylglycerol plasma isozyme, pH 7.5, 22°C Homo sapiens
143
-
 methyl butyrate plasma isozyme, pH 7.5, 22°C Homo sapiens

Localization

Localization Comment Organism GeneOntology No. Textmining
membrane bound, plasma isozyme Homo sapiens 16020
-

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
additional information Homo sapiens plasma isozyme is bound to LDL and HDL particles ?
-
 ?

Organism

Organism UniProt Comment Textmining
Homo sapiens
-
-
-
Physarum sp.
-
-
-

Reaction

Reaction Comment Organism Reaction ID
1-alkyl-2-acetyl-sn-glycero-3-phosphocholine + H2O = 1-alkyl-sn-glycero-3-phosphocholine + acetate stereochemistry Homo sapiens
a
1-alkyl-2-acetyl-sn-glycero-3-phosphocholine + H2O = 1-alkyl-sn-glycero-3-phosphocholine + acetate stereochemistry Physarum sp.
a

Source Tissue

Source Tissue Comment Organism Textmining
plasma plasma isozyme pPAF-AH, and isozyme Ib Homo sapiens
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
1,2-didecanoyl-sn-glycerol + H2O
-
 Homo sapiens ?
-
 ?
1,2-didecanoyl-sn-glycerol + H2O
-
 Physarum sp. ?
-
 ?
1,2-dioctanoyl-sn-glycerol + H2O
-
 Homo sapiens ?
-
 ?
1,2-dioctanoyl-sn-glycerol + H2O
-
 Physarum sp. ?
-
 ?
1,2-dioctanoylethyleneglycol + H2O
-
 Homo sapiens ?
-
 ?
1,2-dioctanoylethyleneglycol + H2O
-
 Physarum sp. ?
-
 ?
1-acetyl-2-hexadecyl-sn-glycero-3-phosphocholine + H2O
-
 Homo sapiens 2-hexadecyl-sn-glycero-3-phosphocholine + acetate
-
 ?
1-acetyl-2-hexadecyl-sn-glycero-3-phosphocholine + H2O
-
 Physarum sp. 2-hexadecyl-sn-glycero-3-phosphocholine + acetate
-
 ?
1-decanoyl-rac-glycerol + H2O
-
 Homo sapiens decanoate + glycerol
-
 ?
1-decanoyl-rac-glycerol + H2O
-
 Physarum sp. ?
-
 ?
1-octanoyl-rac-glycerol + H2O
-
 Homo sapiens octanoate + glycerol
-
 ?
1-octanoyl-rac-glycerol + H2O
-
 Physarum sp. ?
-
 ?
1-oleoyl-2-acetyl-sn-glycerol + H2O
-
 Homo sapiens 1-oleoyl-sn-glycerol + acetate
-
 ?
1-oleoyl-2-acetyl-sn-glycerol + H2O
-
 Physarum sp. 1-oleoyl-sn-glycerol + acetate
-
 ?
2-acetyl-1-hexadecyl-sn-glycero-3-phosphocholine + H2O
-
 Homo sapiens 1-hexadecyl-sn-glycero-3-phosphocholine + acetate
-
 ?
2-acetyl-1-hexadecyl-sn-glycero-3-phosphocholine + H2O
-
 Physarum sp. 1-hexadecyl-sn-glycero-3-phosphocholine + acetate
-
 ?
2-acetyl-1-octadecyl-sn-glycero-3-phosphocholine + H2O
-
 Homo sapiens 1-octadecyl-sn-glycero-3-phosphocholine + acetate
-
 ?
2-acetyl-1-octadecyl-sn-glycero-3-phosphocholine + H2O
-
 Physarum sp. 1-octadecyl-sn-glycero-3-phosphocholine + acetate
-
 ?
2-acetyl-3-octadecyl-sn-glycero-1-phosphocholine + H2O
-
 Homo sapiens 3-octadecyl-sn-glycero-1-phosphocholine + acetate
-
 ?
2-acetyl-3-octadecyl-sn-glycero-1-phosphocholine + H2O
-
 Physarum sp. 3-octadecyl-sn-glycero-1-phosphocholine + acetate
-
 ?
butyl acetate + H2O
-
 Homo sapiens butanol + acetate
-
 ?
butyl acetate + H2O
-
 Physarum sp. butanol + acetate
-
 ?
dibutanoyl-phosphocholine + H2O
-
 Homo sapiens ?
-
 ?
dibutyryl-phosphocholine + H2O
-
 Homo sapiens ?
-
 ?
dibutyryl-phosphocholine + H2O
-
 Physarum sp. ?
-
 ?
didecanoyl-phosphocholine + H2O
-
 Homo sapiens ?
-
 ?
didecanoyl-phosphocholine + H2O
-
 Physarum sp. ?
-
 ?
dioctanoyl-phosphocholine + H2O
-
 Homo sapiens ?
-
 ?
dioctanoyl-phosphocholine + H2O
-
 Physarum sp. ?
-
 ?
methyl butyrate + H2O
-
 Homo sapiens methanol + butyrate
-
 ?
methyl butyrate + H2O
-
 Physarum sp. methanol + butyrate
-
 ?
additional information substrate specificity, overview Physarum sp. ?
-
 ?
additional information substrate specificity of isozymes, overview Homo sapiens ?
-
 ?
additional information plasma isozyme is bound to LDL and HDL particles Homo sapiens ?
-
 ?
octyl acetate + H2O
-
 Homo sapiens octanol + acetate
-
 ?
octyl acetate + H2O
-
 Physarum sp. octanol + acetate
-
 ?
triacetylglycerol + H2O
-
 Homo sapiens diacetylglycerol + acetate
-
 ?
triacetylglycerol + H2O
-
 Physarum sp. diacetylglycerol + acetate
-
 ?
tributyrylglycerol + H2O
-
 Homo sapiens dibutyrylglycerol + butyrate
-
 ?
tributyrylglycerol + H2O
-
 Physarum sp. dibutyrylglycerol + butyrate
-
 ?
trioctanoylglycerol + H2O
-
 Homo sapiens dioctanoylglycerol + octanoate
-
 ?
trioctanoylglycerol + H2O
-
 Physarum sp. dioctanoylglycerol + octanoate
-
 ?

Synonyms

Synonyms Comment Organism
PAF-AH
-
 Homo sapiens
PAF-AH
-
 Physarum sp.
platelet-activating factor acetylhydrolase
-
 Homo sapiens
platelet-activating factor acetylhydrolase
-
 Physarum sp.

Temperature Optimum [°C]

Temperature Optimum [°C] Temperature Optimum Maximum [°C] Comment Organism
22
-
 assay at Homo sapiens

Turnover Number [1/s]

Turnover Number Minimum [1/s] Turnover Number Maximum [1/s] Substrate Comment Organism Structure
0.25
-
 1-oleoyl-2-acetyl-sn-glycerol isozyme Ib, (alpha2)2 subunit, pH 7.5, 22°C Homo sapiens
0.28
-
 octyl acetate plasma isozyme, pH 7.5, 22°C Homo sapiens
0.34
-
 2-acetyl-1-hexadecyl-sn-glycero-3-phosphocholine isozyme Ib, (alpha1)2 subunit, pH 7.5, 22°C Homo sapiens
0.68
-
 2-acetyl-1-octadecyl-sn-glycero-3-phosphocholine isozyme Ib, (alpha2)2 subunit, pH 7.5, 22°C Homo sapiens
0.69
-
 octyl acetate isozyme Ib, (alpha1)2 subunit, pH 7.5, 22°C Homo sapiens
1.1
-
 1-acetyl-2-hexadecyl-sn-glycero-3-phosphocholine isozyme Ib, (alpha2)2 subunit, pH 7.5, 22°C Homo sapiens
1.7
-
 triacetylglycerol isozyme Ib, (alpha1)2 subunit, pH 7.5, 22°C Homo sapiens
1.9
-
 octyl acetate isozyme Ib, (alpha2)2 subunit, pH 7.5, 22°C Homo sapiens
3
-
 1-oleoyl-2-acetyl-sn-glycerol plasma isozyme, pH 7.5, 22°C Homo sapiens
3.2
-
 2-acetyl-1-hexadecyl-sn-glycero-3-phosphocholine isozyme Ib, (alpha2)2 subunit, pH 7.5, 22°C Homo sapiens
4.8
-
 2-acetyl-1-octadecyl-sn-glycero-3-phosphocholine plasma isozyme, pH 7.5, 22°C Homo sapiens
6.08
-
 octyl acetate isozyme Ib, (alpha1)2 subunit, pH 7.5, 22°C Homo sapiens
6.08
-
 2-acetyl-1-octadecyl-sn-glycero-3-phosphocholine isozyme Ib, (alpha2)2 subunit, pH 7.5, 22°C Homo sapiens
8.1
-
 1-acetyl-2-hexadecyl-sn-glycero-3-phosphocholine plasma isozyme, pH 7.5, 22°C Homo sapiens
16.5
-
 triacetylglycerol plasma isozyme, pH 7.5, 22°C Homo sapiens
24.6
-
 2-acetyl-1-hexadecyl-sn-glycero-3-phosphocholine plasma isozyme, pH 7.5, 22°C Homo sapiens
37
-
 triacetylglycerol isozyme Ib, (alpha2)2 subunit, pH 7.5, 22°C Homo sapiens

pH Optimum

pH Optimum Minimum pH Optimum Maximum Comment Organism
7.5
-
 assay at Homo sapiens