Cloned (Comment) | Organism |
---|---|
PLA2 injected (subcutaneous) into the right hind paw of mice | Naja naja |
Inhibitors | Comment | Organism | Structure |
---|---|---|---|
turmerin | inhibits the enzymatic activity and neutralises the pharmacological properties, such as cytotoxicity, oedema and myotoxicity of multitoxic phospholipase A2 of cobra venom in a dose-dependent manner, at a 1:2.5 molar ratio of PLA2:turmerin | Naja naja |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Naja naja | - |
- |
- |
Purification (Comment) | Organism |
---|---|
by gel filtration | Naja naja |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
venom | - |
Naja naja | - |
Synonyms | Comment | Organism |
---|---|---|
phospholipase A2 | - |
Naja naja |
PLA2 | - |
Naja naja |
General Information | Comment | Organism |
---|---|---|
physiological function | PLA2 induces cytotoxic effect on human peripheral lymphocytes. Increased creatine kinase levels (myonecrosis) in the group of mice treated with PLA2 | Naja naja |